MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	Ratio	description	Class	Gene	Gene Ontology	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 593 to 642 of 2667 in total

Regulation  : down

Ratio	description	Class	Gene Ontology
1.58045	Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3). [Uniprot/SWISSPROT;Acc:P56589]	biological process	peroxisome organization and biogenesis
		cellular component	integral to peroxisomal membrane
			integral to plasma membrane
			membrane
			peroxisomal membrane
			peroxisome
		molecular function	protein binding
1.59763	Ubiquitin-conjugating enzyme E2 Q2 (EC 6.3.2.19) (Ubiquitin-protein ligase Q2) (Ubiquitin carrier protein Q2). [Uniprot/SWISSPROT;Acc:Q8WVN8]	biological process	protein modification process
			ubiquitin cycle
		cellular component	cytoplasm
		molecular function	ATP binding
			ligase activity
			nucleotide binding
			small conjugating protein ligase activity
			ubiquitin-protein ligase activity
1.60746	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Uniprot/SWISSPROT;Acc:Q8TD26]	biological process	chromatin assembly or disassembly
			chromatin remodeling
			nervous system development
			nucleosome assembly
			regulation of transcription, DNA-dependent
			response to antibiotic
			tetracycline transport
			transcription
		cellular component	chromatin
			integral to membrane
			nucleosome
			nucleus
		molecular function	ATP binding
			ATP-dependent helicase activity
			chromatin binding
			DNA binding
			helicase activity
			hydrolase activity
			nucleic acid binding
			nucleotide binding
			tetracycline:hydrogen antiporter activity
1.61347	Calmodulin-like protein 5 (Calmodulin-like skin protein). [Uniprot/SWISSPROT;Acc:Q9NZT1]	biological process	ciliary or flagellar motility
			epidermis development
			signal transduction
		cellular component	flagellin-based flagellum
		molecular function	calcium ion binding
			protein binding
1.65835	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific). [Uniprot/SWISSPROT;Acc:P57772]	biological process	selenocysteine incorporation
			translational elongation
		cellular component	cytoplasm
			nucleus
		molecular function	GTP binding
			GTPase activity
			nucleotide binding
			translation elongation factor activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.