MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 593 to 642 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein). [Uniprot/SWISSPROT;Acc:Q9P232]	3.99682	down	biological process	cell adhesion
				protein amino acid phosphorylation
			cellular component	membrane
			molecular function	ATP binding
				GPI anchor binding
				interleukin-1 receptor activity
				protein binding
				vascular endothelial growth factor receptor activity
COX16-like protein C14orf112, mitochondrial precursor. [Uniprot/SWISSPROT;Acc:Q9P0S2]	1.40451		cellular component	integral to membrane
				membrane
				mitochondrion
Cullin-4B (CUL-4B). [Uniprot/SWISSPROT;Acc:Q13620]	1.49271		biological process	cell cycle
				DNA repair
				ubiquitin cycle
			cellular component	cellular_component
			molecular function	molecular_function
				protein binding
Cyclin-A2 (Cyclin-A). [Uniprot/SWISSPROT;Acc:P20248]	1.45635	up	biological process	cell cycle
				cell division
				mitosis
				mitotic G2 checkpoint
				positive regulation of transcription
				regulation of cyclin-dependent protein kinase activity
				regulation of progression through cell cycle
			cellular component	cytoplasm
				female pronucleus
				male pronucleus
				nucleus
			molecular function	protein binding
Cyclin-I. [Uniprot/SWISSPROT;Acc:Q14094]	1.36349	down	biological process	regulation of progression through cell cycle
				spermatogenesis
Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7). [Uniprot/SWISSPROT;Acc:Q9Y697]	1.19539	up		amino acid metabolic process
				metabolic process
				protein complex assembly
				sulfur amino acid metabolic process
			cellular component	cytoplasm
				cytosol
				mitochondrion
				nucleus
			molecular function	catalytic activity
				cysteine desulfurase activity
				lyase activity
				pyridoxal phosphate binding
				transaminase activity
				transferase activity
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia). [Uniprot/SWISSPROT;Acc:Q9UKJ5]	1.63639		biological process	biological_process
			cellular component	cellular_component
				cytoplasmic vesicle
				Golgi apparatus
				Golgi-associated vesicle

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.