MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 540 to 589 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Claudin-11 (Oligodendrocyte-specific protein). [Uniprot/SWISSPROT;Acc:O75508]	1.75026	up	cellular component	cell junction
				integral to membrane
				membrane
				tight junction
			molecular function	identical protein binding
				structural molecule activity
CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (hOrbit2). [Uniprot/SWISSPROT;Acc:O75122]	1.29151		biological process	cell cycle
				cell division
				establishment and/or maintenance of cell polarity
				mitosis
				negative regulation of microtubule depolymerization
				regulation of microtubule polymerization or depolymerization
			cellular component	cytoplasm
				cytoplasmic microtubule
				cytoskeleton
				Golgi apparatus
				kinetochore microtubule
			molecular function	binding
				galactoside 2-alpha-L-fucosyltransferase activity
				microtubule binding
				microtubule plus-end binding
				protein binding
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (Gal-NAc6S) (STZ) (SIAT4-C) (ST3Gal III) (SAT-3) (ST-4). [Uniprot/SWISSPROT;Acc:Q11206]	1.69658	down	biological process	protein amino acid glycosylation
			cellular component	Golgi apparatus
				integral to Golgi membrane
				integral to membrane
				membrane
			molecular function	beta-galactoside alpha-2,3-sialyltransferase activity
				sialyltransferase activity
				transferase activity, transferring glycosyl groups
Coiled-coil and C2 domain-containing protein 1B. [Uniprot/SWISSPROT;Acc:Q5T0F9]	1.29238	up		FAD binding
				oxidoreductase activity
coiled-coil domain containing 90A [RefSeq_peptide;Acc:NP_001026883]	1.83601		biological process	G-protein coupled receptor protein signaling pathway
			cellular component	integral to membrane
				membrane
				mitochondrion
Coiled-coil domain-containing protein 108. [Uniprot/SWISSPROT;Acc:Q6ZU64]	1.72628	down	biological process	DNA repair
			cellular component	integral to membrane
				membrane
			molecular function	methylated-DNA-[protein]-cysteine S-methyltransferase activity
				structural molecule activity
Coiled-coil domain-containing protein 83. [Uniprot/SWISSPROT;Acc:Q8IWF9]	2.37788	up	cellular component	viral capsid
			molecular function	structural molecule activity
collagen, type XXVII, alpha 1 [RefSeq_peptide;Acc:NP_116277]	1.40749		biological process	cell adhesion
				G-protein coupled receptor protein signaling pathway
				phosphate transport
			cellular component	collagen
				cytoplasm
				integral to membrane
			molecular function	dopamine receptor activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.