MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Regulation	Accession	Gene Ontology	Gene	Class	Ratio	Maximum Ratio	Minimum Ratio

Results: HTML CSV LaTeX

Showing element 501 to 550 of 2667 in total

Regulation  : up

description	Gene Ontology	Class	Ratio
Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Uniprot/SWISSPROT;Acc:Q9P2D1]	female genitalia development	biological process	1.25808
	heart morphogenesis
	helicase activity	molecular function
	hydrolase activity
	in utero embryonic development	biological process
	inner ear morphogenesis
	locomotory behavior
	nose development
	nucleic acid binding	molecular function
	nucleotide binding
	nucleus	cellular component
	palate development	biological process
	positive regulation of body size
	regulation of transcription, DNA-dependent
	sensory perception of sound
	transcription
Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18). [Uniprot/SWISSPROT;Acc:O95232]	apoptosis		2.91954
	DNA binding	molecular function
	nucleus	cellular component
	protein binding	molecular function
	response to stress	biological process
	RNA splicing
CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4). [Uniprot/SWISSPROT;Acc:Q8IZR5]	ATP binding	molecular function	1.86433
	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
	cation transport	biological process
	chemotaxis
	cytokine activity	molecular function
	extracellular space	cellular component
	integral to membrane
	membrane
Clarin-1 (Usher syndrome type-3 protein). [Uniprot/SWISSPROT;Acc:P58418]	integral to membrane		4.05743
	membrane
	response to stimulus	biological process
	sensory perception of sound
	visual perception
Claudin-11 (Oligodendrocyte-specific protein). [Uniprot/SWISSPROT;Acc:O75508]	axon ensheathment		1.75026
	calcium-independent cell-cell adhesion
	cell adhesion
	cell junction	cellular component
	identical protein binding	molecular function
	integral to membrane	cellular component
	membrane
	spermatogenesis	biological process
	structural molecule activity	molecular function
	tight junction	cellular component
CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (hOrbit2). [Uniprot/SWISSPROT;Acc:O75122]	binding	molecular function	1.29151
	cell cycle	biological process
	cell division
	cytoplasm	cellular component
	cytoplasmic microtubule

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.