MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 501 to 550 of 688 in total

Class  : cellular component

description	Ratio	Regulation	Gene Ontology
Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). [Uniprot/SWISSPROT;Acc:Q13905]	1.49923	down	intracellular
RAS-like, family 11, member A [RefSeq_peptide;Acc:NP_996563]	1.7961	up
Ras-related GTP-binding protein D (Rag D). [Uniprot/SWISSPROT;Acc:Q9NQL2]	1.19117		cytoplasm
			nucleus
Ras-related protein Rab-17. [Uniprot/SWISSPROT;Acc:Q9H0T7]	1.95876		intracellular
Ras-related protein Rab-36. [Uniprot/SWISSPROT;Acc:O95755]	1.89308		Golgi apparatus
			intracellular
			membrane
Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon). [Uniprot/SWISSPROT;Acc:P23469]	4.03725		cytoplasm
			integral to plasma membrane
			membrane
			soluble fraction
Rho GTPase-activating protein 24 (Rho-type GTPase-activating protein 24) (Filamin-A-associated RhoGAP) (FilGAP) (p73RhoGAP) (RhoGAP of 73 kDa) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Sarcoma antigen NY-SAR-88). [Uniprot/SWISSPROT;Acc:Q8N264]	1.36997		cell junction
			cytoplasm
			cytoskeleton
			intracellular
			membrane
Rho-related BTB domain-containing protein 1. [Uniprot/SWISSPROT;Acc:O94844]	5.31521		intracellular
Rhophilin-1 (GTP-Rho-binding protein 1). [Uniprot/SWISSPROT;Acc:Q8TCX5]	1.80858	down
Ribonuclease P protein subunit p29 (EC 3.1.26.5) (hPOP4). [Uniprot/SWISSPROT;Acc:O95707]	2.12709		nucleus
			ribonuclease MRP complex
			ribonuclease P complex
RIM-binding protein 2 (RIM-BP2). [Uniprot/SWISSPROT;Acc:O15034]	2.27115		cell junction
			membrane
			synapse
RING finger protein 170 (Putative LAG1-interacting protein). [Uniprot/SWISSPROT;Acc:Q96K19]	5.61927		integral to membrane
			membrane
RNA polymerase-associated protein RTF1 homolog. [Uniprot/SWISSPROT;Acc:Q92541]	3.35536	up	nucleolus
			nucleus
RNA-binding protein 28 (RNA-binding motif protein 28). [Uniprot/SWISSPROT;Acc:Q9NW13]	2.86965		chromosome
			nucleus
RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (hLark). [Uniprot/SWISSPROT;Acc:Q9BWF3]	1.42264		cytoplasm
			intracellular
			nucleus
			ribosome
SAC3 domain containing 1 [RefSeq_peptide;Acc:NP_037431]	2.75048		centrosome
			spindle
Sad1/unc-84-like protein 2 (Rab5-interacting protein) (Rab5IP). [Uniprot/SWISSPROT;Acc:Q9UH99]	4.04651		condensed nuclear chromosome
			endosome
			integral to membrane
			membrane
			nuclear chromosome, telomeric region
			nuclear envelope
			nucleus
Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide]. [Uniprot/SWISSPROT;Acc:P05060]	4.49844	down	extracellular space
Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific). [Uniprot/SWISSPROT;Acc:P57772]	1.65835		cytoplasm
			nucleus
Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1). [Uniprot/SWISSPROT;Acc:Q99719]	1.21657	up	plasma membrane
			synaptic vesicle
			synaptosome

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.