MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Accession	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 451 to 500 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta). [Uniprot/SWISSPROT;Acc:Q14839]	1.78439	up	biological process	regulation of transcription from RNA polymerase II promoter
				transcription
			cellular component	chromatin
				nucleus
			molecular function	ATP binding
				ATP-dependent DNA helicase activity
				ATP-dependent helicase activity
				chromatin binding
				DNA binding
				helicase activity
				hydrolase activity
				metal ion binding
				nucleic acid binding
				nucleotide binding
				protein binding
				transcription factor binding
				zinc ion binding
Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Uniprot/SWISSPROT;Acc:Q8TD26]	1.60746	down	biological process	chromatin assembly or disassembly
				chromatin remodeling
				nervous system development
				nucleosome assembly
				regulation of transcription, DNA-dependent
				response to antibiotic
				tetracycline transport
				transcription
			cellular component	chromatin
				integral to membrane
				nucleosome
				nucleus
			molecular function	ATP binding
				ATP-dependent helicase activity
				chromatin binding
				DNA binding
				helicase activity
				hydrolase activity
				nucleic acid binding
				nucleotide binding
				tetracycline:hydrogen antiporter activity
Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Uniprot/SWISSPROT;Acc:Q9P2D1]	1.25808	up	biological process	adult heart development
				adult walking behavior
				blood vessel development
				camera-type eye development
				chromatin assembly or disassembly
				chromatin modification
				circulation
				embryonic hindlimb morphogenesis
				female genitalia development
				heart morphogenesis
				in utero embryonic development
				inner ear morphogenesis

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.