MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 440 to 489 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Chloride anion exchanger (Protein DRA) (Down-regulated in adenoma) (Solute carrier family 26 member 3). [Uniprot/SWISSPROT;Acc:P40879]	1.31661	up	molecular function	antiporter activity
				chloride ion binding
				heme transporter activity
				sulfate porter activity
				transcription cofactor activity
				transcription factor activity
				transporter activity
Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta). [Uniprot/SWISSPROT;Acc:Q14839]	1.78439		biological process	chromatin assembly or disassembly
				chromatin modification
				chromosome organization and biogenesis (sensu Eukaryota)
				intracellular signaling cascade
				regulation of transcription from RNA polymerase II promoter
				transcription
			cellular component	chromatin
				nucleus
			molecular function	ATP binding
				ATP-dependent DNA helicase activity
				ATP-dependent helicase activity
				chromatin binding
				DNA binding
				helicase activity
				hydrolase activity
				metal ion binding
				nucleic acid binding
				nucleotide binding
				protein binding
				transcription factor binding
				zinc ion binding
Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Uniprot/SWISSPROT;Acc:Q8TD26]	1.60746	down	biological process	chromatin assembly or disassembly
				chromatin remodeling
				nervous system development
				nucleosome assembly
				regulation of transcription, DNA-dependent
				response to antibiotic
				tetracycline transport
				transcription
			cellular component	chromatin
				integral to membrane
				nucleosome
				nucleus
			molecular function	ATP binding
				ATP-dependent helicase activity
				chromatin binding
				DNA binding
				helicase activity
				hydrolase activity
				nucleic acid binding
				nucleotide binding
				tetracycline:hydrogen antiporter activity
Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Uniprot/SWISSPROT;Acc:Q9P2D1]	1.25808	up	biological process	adult heart development

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.