MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Gene Ontology	Regulation	Class	Accession	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 401 to 450 of 2667 in total

description	Ratio	Gene Ontology	Regulation	Class
CDNA: FLJ22222 fis, clone HRC01658. [Uniprot/SPTREMBL;Acc:Q9H6J2]	1.32602	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	down	molecular function
		protein metabolic process		biological process
Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein). [Uniprot/SWISSPROT;Acc:Q8WZ64]	1.23783	cytoplasm		cellular component
		GTPase activator activity		molecular function
		intracellular		cellular component
		metal ion binding		molecular function
		phosphatidylinositol-3,4,5-triphosphate binding
		regulation of GTPase activity		biological process
		signal transduction
		zinc ion binding		molecular function
Centromere protein L (CENP-L) (Interphase centromere complex protein 33). [Uniprot/SWISSPROT;Acc:Q8N0S6]	1.78708	chromosome	up	cellular component
		chromosome, pericentric region
		nucleus
Centromere protein S (CENP-S) (Apoptosis-inducing TAF9-like domain- containing protein 1). [Uniprot/SWISSPROT;Acc:Q8N2Z9]	2.7017	chromosome
		chromosome organization and biogenesis (sensu Eukaryota)		biological process
		chromosome, pericentric region		cellular component
		DNA binding		molecular function
		extracellular region		cellular component
		G-protein signaling, adenylate cyclase inhibiting pathway		biological process
		G-protein-coupled receptor binding		molecular function
		hormone activity
		neuropeptide hormone activity
		nucleosome		cellular component
		nucleosome assembly		biological process
		nucleus		cellular component
		soluble fraction
		synaptic transmission		biological process
Chloride anion exchanger (Protein DRA) (Down-regulated in adenoma) (Solute carrier family 26 member 3). [Uniprot/SWISSPROT;Acc:P40879]	1.31661	anion exchanger activity		molecular function
		anion transport		biological process
		antiporter activity		molecular function
		apical plasma membrane		cellular component
		brush border membrane
		chloride ion binding		molecular function
		cytochrome complex assembly		biological process
		excretion
		heme transport
		heme transporter activity		molecular function
		integral to membrane		cellular component
		membrane
		membrane fraction
		sulfate porter activity		molecular function
		sulfate transport		biological process
		transcription cofactor activity		molecular function
		transcription factor activity
		transport		biological process
		transporter activity		molecular function
Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta). [Uniprot/SWISSPROT;Acc:Q14839]	1.78439	ATP binding
		ATP-dependent DNA helicase activity
		ATP-dependent helicase activity
		chromatin		cellular component

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.