MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene Ontology	Class	Regulation	Gene	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 351 to 400 of 2667 in total

description	Ratio	Gene Ontology	Class	Regulation
Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D). [Uniprot/SWISSPROT;Acc:O15438]	1.30802	nucleoside-triphosphatase activity	molecular function	down
		nucleotide binding
		organic anion transporter activity
		transport	biological process
		transporter activity	molecular function
Carboxypeptidase A2 precursor (EC 3.4.17.15). [Uniprot/SWISSPROT;Acc:P48052]	1.43351	carboxypeptidase A activity
		carboxypeptidase activity
		metal ion binding
		metallopeptidase activity
		proteolysis	biological process
		vacuolar protein catabolic process
		zinc ion binding	molecular function
Cartilage acidic protein 1 precursor (68 kDa chondrocyte-expressed protein) (CEP-68) (ASPIC). [Uniprot/SWISSPROT;Acc:Q9NQ79]	2.70687	calcium ion binding		up
		homoiothermy	biological process
		ice binding	molecular function
		intracellular	cellular component
		response to freezing	biological process
		ribosome	cellular component
		structural constituent of ribosome	molecular function
		translation	biological process
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2). [Uniprot/SWISSPROT;Acc:Q9NZN8]	1.30082	cytoplasm	cellular component	down
		nucleus
		regulation of global transcription from RNA polymerase II promoter	biological process
		regulation of transcription
		regulation of transcription, DNA-dependent
		RNA polymerase II transcription mediator activity	molecular function
		transcription regulator activity
CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1). [Uniprot/SWISSPROT;Acc:Q8IX05]	2.88128	integral to membrane	cellular component
		membrane
		sugar binding	molecular function
CD40 ligand (CD40-L) (Tumor necrosis factor ligand superfamily member 5) (TNF-related activation protein) (TRAP) (T cell antigen Gp39) (CD154 antigen) [Contains: CD40 ligand, membrane form; CD40 ligand, soluble form]. [Uniprot/SWISSPROT;Acc:P29965]	1.98149	anti-apoptosis	biological process	up
		B cell differentiation
		B cell proliferation
		CD40 receptor binding	molecular function
		cytokine activity
		extracellular space	cellular component
		immune response	biological process
		inflammatory response
		integral to membrane	cellular component
		integral to plasma membrane
		isotype switching	biological process
		leukocyte adhesion
		membrane	cellular component
		platelet activation	biological process
		regulation of immunoglobulin secretion
		soluble fraction	cellular component
		tumor necrosis factor receptor binding	molecular function
CDK5 regulatory subunit associated protein 1-like 1 [RefSeq_peptide;Acc:NP_060244]	1.693	catalytic activity		down
		iron-sulfur cluster binding
		metabolic process	biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.