MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Gene	Gene Ontology	Class	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2619 to 2667 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Trinucleotide repeat-containing gene 1 protein). [Uniprot/SWISSPROT;Acc:Q8TF68]	1.59188	up	DNA binding	molecular function
			intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription
			zinc ion binding	molecular function
Zinc finger protein basonuclin-2. [Uniprot/SWISSPROT;Acc:Q6ZN30]	1.1243	down	DNA binding
			intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription
			zinc ion binding	molecular function
Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146). [Uniprot/SWISSPROT;Acc:Q15072]	1.25113		DNA binding
			heparin binding
			intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			zinc ion binding	molecular function
Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Uniprot/SWISSPROT;Acc:Q92785]	1.93995	up	apoptosis	biological process
			cytoplasm	cellular component
			induction of apoptosis by extracellular signals	biological process
			intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			protein binding	molecular function
			regulation of transcription, DNA-dependent	biological process
			transcription
			zinc ion binding	molecular function
Zinc finger SWIM domain-containing protein 3. [Uniprot/SWISSPROT;Acc:Q96MP5]	1.56335		metal ion binding
			zinc ion binding
zinc finger, FYVE domain containing 26 [RefSeq_peptide;Acc:NP_056161]	4.87049		intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			zinc ion binding
zinc transporter like 2 [RefSeq_peptide;Acc:NP_598003]	2.45764		cation transport	biological process
			cation transporter activity	molecular function
			cytoplasmic membrane-bound vesicle	cellular component
			Golgi apparatus
			membrane
			protein binding	molecular function
			zinc ion transport	biological process
			zinc ion transporter activity	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.