MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	description	Ratio	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2619 to 2667 of 2667 in total

Regulation  : up

description	Ratio	Gene Ontology	Class
Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamma-7 subunit). [Uniprot/SWISSPROT;Acc:P62955]	3.41415	voltage-gated calcium channel activity	molecular function
		voltage-gated calcium channel complex	cellular component
		voltage-gated ion channel activity	molecular function
Zinc finger protein 219. [Uniprot/SWISSPROT;Acc:Q9P2Y4]	1.13007	anion transport	biological process
		G-protein coupled receptor protein signaling pathway
		histamine receptor activity	molecular function
		inorganic anion exchanger activity
		integral to membrane	cellular component
		intracellular
		membrane
		metal ion binding	molecular function
		nucleic acid binding
		nucleus	cellular component
		regulation of transcription, DNA-dependent	biological process
		transcription factor activity	molecular function
		zinc ion binding
Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Trinucleotide repeat-containing gene 1 protein). [Uniprot/SWISSPROT;Acc:Q8TF68]	1.59188	DNA binding
		intracellular	cellular component
		metal ion binding	molecular function
		nucleic acid binding
		nucleus	cellular component
		regulation of transcription, DNA-dependent	biological process
		transcription
		zinc ion binding	molecular function
Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Uniprot/SWISSPROT;Acc:Q92785]	1.93995	apoptosis	biological process
		cytoplasm	cellular component
		induction of apoptosis by extracellular signals	biological process
		intracellular	cellular component
		metal ion binding	molecular function
		nucleic acid binding
		nucleus	cellular component
		protein binding	molecular function
		regulation of transcription, DNA-dependent	biological process
		transcription
		zinc ion binding	molecular function
Zinc finger SWIM domain-containing protein 3. [Uniprot/SWISSPROT;Acc:Q96MP5]	1.56335	metal ion binding
		zinc ion binding
zinc finger, FYVE domain containing 26 [RefSeq_peptide;Acc:NP_056161]	4.87049	intracellular	cellular component
		metal ion binding	molecular function
		nucleic acid binding
		zinc ion binding
zinc transporter like 2 [RefSeq_peptide;Acc:NP_598003]	2.45764	cation transport	biological process
		cation transporter activity	molecular function
		cytoplasmic membrane-bound vesicle	cellular component
		Golgi apparatus
		membrane
		protein binding	molecular function
		zinc ion transport	biological process
		zinc ion transporter activity	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.