Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description Ratio Regulation Gene Gene Ontology Class Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2569 to 2618 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu). [Uniprot/SWISSPROT;Acc:P30291]	1.48363	down	protein binding	molecular function
			protein kinase activity
			protein serine/threonine kinase activity
			protein-tyrosine kinase activity
			regulation of progression through cell cycle	biological process
			transferase activity	molecular function
X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5). [Uniprot/SWISSPROT;Acc:P17861]	4.4149		DNA binding	molecular function
			immune response	biological process
			nucleus	cellular component
			protein dimerization activity	molecular function
			regulation of transcription	biological process
			regulation of transcription, DNA-dependent	biological process
			sequence-specific DNA binding	molecular function
			transcription	biological process
			transcription factor activity	molecular function
XK-related protein 5. [Uniprot/SWISSPROT;Acc:Q6UX68]	1.17859		integral to membrane	cellular component
XK-related protein 5. [Uniprot/SWISSPROT;Acc:Q6UX68]	1.17859		membrane
Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494). [Uniprot/SWISSPROT;Acc:Q8NAM6]	1.86204		intracellular
			metal ion binding	molecular function
			nucleic acid binding	molecular function
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription	biological process
			transcription factor activity	molecular function
			zinc ion binding
Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Uniprot/SWISSPROT;Acc:O95125]	1.89168		DNA binding
			intracellular	cellular component
			lipid metabolic process	biological process
			metal ion binding	molecular function
			negative regulation of transcription from RNA polymerase II promoter	biological process
			nucleic acid binding	molecular function
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			specific RNA polymerase II transcription factor activity	molecular function
			transcription	biological process
			transcription factor activity	molecular function
			zinc ion binding	molecular function
Zinc finger protein 219. [Uniprot/SWISSPROT;Acc:Q9P2Y4]	1.13007	up	anion transport	biological process
			G-protein coupled receptor protein signaling pathway	biological process
			histamine receptor activity	molecular function
			inorganic anion exchanger activity	molecular function
			integral to membrane	cellular component
			intracellular
			membrane
			metal ion binding	molecular function
			nucleic acid binding	molecular function
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription factor activity	molecular function
			zinc ion binding	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/