MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	description	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2540 to 2589 of 2667 in total

Ratio	Regulation	description	Class	Gene Ontology
5.01332	up	Ufm1-specific protease 2 (EC 3.4.22.-) (UfSP2). [Uniprot/SWISSPROT;Acc:Q9NUQ7]	biological process	ubiquitin cycle
			molecular function	cysteine-type peptidase activity
				thiolester hydrolase activity
5.19755		Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Uniprot/SWISSPROT;Acc:Q96A54]	biological process	fatty acid oxidation
				hormone-mediated signaling
				lipid metabolic process
			cellular component	integral to membrane
				membrane
			molecular function	hormone binding
				identical protein binding
				protein heterodimerization activity
				receptor activity
5.23046	down	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K). [Uniprot/SWISSPROT;Acc:P48736]	biological process	G-protein coupled receptor protein signaling pathway
				negative regulation of apoptosis
				phosphoinositide phosphorylation
				phosphoinositide-mediated signaling
				protein amino acid phosphorylation
			cellular component	phosphoinositide 3-kinase complex
			molecular function	1-phosphatidylinositol-3-kinase activity
				inositol or phosphatidylinositol kinase activity
				phosphatidylinositol-4,5-bisphosphate 3-kinase activity
				phosphotransferase activity, alcohol group as acceptor
				protein binding
				transferase activity
5.31521	up	Rho-related BTB domain-containing protein 1. [Uniprot/SWISSPROT;Acc:O94844]	biological process	protein transport
				small GTPase mediated signal transduction
			cellular component	intracellular
			molecular function	GTP binding
				nucleotide binding
				protein binding
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Uniprot/SWISSPROT;Acc:Q12968]	biological process	cellular respiration
				heart development
				inflammatory response
				regulation of transcription
				regulation of transcription from RNA polymerase II promoter
				regulation of transcription, DNA-dependent
			cellular component	cytoplasm
				nucleus
			molecular function	protein binding
				transcription coactivator activity
				transcription factor activity
5.53059	up	rab and DnaJ domain containing [RefSeq_peptide;Acc:NP_057628]	biological process	intracellular protein transport
				nucleocytoplasmic transport
				protein transport
				signal transduction
				small GTPase mediated signal transduction
			cellular component	intracellular
			molecular function	GTP binding
				GTPase activity
				heat shock protein binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.