MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Regulation	Ratio	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2401 to 2450 of 2667 in total

description	Regulation	Ratio	Gene Ontology	Class
Transcription factor E2F3 (E2F-3). [Uniprot/SWISSPROT;Acc:O00716]	up	3.81736	transcription initiation from RNA polymerase II promoter	biological process
Transcription factor GATA-6 (GATA-binding factor 6). [Uniprot/SWISSPROT;Acc:Q92908]	down	3.29064	chromatin binding	molecular function
			DNA binding
			liver development	biological process
			metal ion binding	molecular function
			muscle development	biological process
			nucleus	cellular component
			positive regulation of transcription	biological process
			positive regulation of transcription from RNA polymerase II promoter
			protein binding	molecular function
			regulation of transcription, DNA-dependent	biological process
			RNA polymerase II transcription factor activity, enhancer binding	molecular function
			sequence-specific DNA binding
			transcription	biological process
			transcription factor activity	molecular function
			transcriptional activator activity
			zinc ion binding
Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2). [Uniprot/SWISSPROT;Acc:Q16621]	up	1.45624	circulation	biological process
			DNA binding	molecular function
			hemostasis	biological process
			multicellular organismal development
			nucleus	cellular component
			protein dimerization activity	molecular function
			regulation of transcription	biological process
			regulation of transcription from RNA polymerase II promoter
			regulation of transcription, DNA-dependent
			sequence-specific DNA binding	molecular function
			transcription coactivator activity
			transcription factor activity
Transcription factor SOX-14. [Uniprot/SWISSPROT;Acc:O95416]		4.55177	chromatin	cellular component
			DNA binding	molecular function
			establishment and/or maintenance of chromatin architecture	biological process
			nervous system development
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription
			transcription factor activity	molecular function
Transgelin-2 (SM22-alpha homolog). [Uniprot/SWISSPROT;Acc:P37802]		1.59177	actin binding
			actomyosin structure organization and biogenesis	biological process
			muscle development
			protein binding	molecular function
Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC [Uniprot/SWISSPROT;Acc:Q9HBA0]		1.60668	calcium channel activity
			calcium ion binding
			calcium ion homeostasis	biological process
			calcium ion transport
			calmodulin binding	molecular function
			identical protein binding
			integral to membrane	cellular component
			ion channel activity	molecular function
			ion transport	biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.