MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Regulation	description	Ratio	Class	Gene Ontology	Gene	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 240 to 289 of 2667 in total

Regulation  : down

description	Ratio	Class	Gene Ontology
CDK5 regulatory subunit associated protein 1-like 1 [RefSeq_peptide;Acc:NP_060244]	1.693	biological process	metabolic process
		molecular function	catalytic activity
			iron-sulfur cluster binding
CDNA: FLJ22222 fis, clone HRC01658. [Uniprot/SPTREMBL;Acc:Q9H6J2]	1.32602	biological process	protein metabolic process
		molecular function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein). [Uniprot/SWISSPROT;Acc:Q8WZ64]	1.23783	biological process	regulation of GTPase activity
			signal transduction
		cellular component	cytoplasm
			intracellular
		molecular function	GTPase activator activity
			metal ion binding
			phosphatidylinositol-3,4,5-triphosphate binding
			zinc ion binding
Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Uniprot/SWISSPROT;Acc:Q8TD26]	1.60746	biological process	chromatin assembly or disassembly
			chromatin remodeling
			nervous system development
			nucleosome assembly
			regulation of transcription, DNA-dependent
			response to antibiotic
			tetracycline transport
			transcription
		cellular component	chromatin
			integral to membrane
			nucleosome
			nucleus
		molecular function	ATP binding
			ATP-dependent helicase activity
			chromatin binding
			DNA binding
			helicase activity
			hydrolase activity
			nucleic acid binding
			nucleotide binding
			tetracycline:hydrogen antiporter activity
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (Gal-NAc6S) (STZ) (SIAT4-C) (ST3Gal III) (SAT-3) (ST-4). [Uniprot/SWISSPROT;Acc:Q11206]	1.69658	biological process	protein amino acid glycosylation
		cellular component	Golgi apparatus
			integral to Golgi membrane
			integral to membrane
			membrane
		molecular function	beta-galactoside alpha-2,3-sialyltransferase activity
			sialyltransferase activity
			transferase activity, transferring glycosyl groups
Coiled-coil domain-containing protein 108. [Uniprot/SWISSPROT;Acc:Q6ZU64]	1.72628	biological process	DNA repair
		cellular component	integral to membrane
			membrane
		molecular function	methylated-DNA-[protein]-cysteine S-methyltransferase activity
			structural molecule activity
Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein). [Uniprot/SWISSPROT;Acc:Q9P232]	3.99682	biological process	cell adhesion
			protein amino acid phosphorylation
		cellular component	membrane

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.