MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2301 to 2350 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7). [Uniprot/SWISSPROT;Acc:Q7Z3E1]	1.66679	up	cellular component	nucleus
			molecular function	metal ion binding
				NAD+ ADP-ribosyltransferase activity
				nucleic acid binding
				protein binding
				transferase activity, transferring glycosyl groups
				zinc ion binding
Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8) (Tetraspanin TM4-A). [Uniprot/SWISSPROT;Acc:O60637]	3.07625	down	biological process	cell motility
				cell proliferation
			cellular component	integral to membrane
				membrane
Tetratricopeptide repeat protein 18 (TPR repeat protein 18). [Uniprot/SWISSPROT;Acc:Q5T0N1]	1.58115	up	molecular function	binding
THO complex subunit 2 (Tho2). [Uniprot/SWISSPROT;Acc:Q8NI27]	1.28698		biological process	mRNA processing
				mRNA transport
				RNA splicing
				transport
			cellular component	nucleus
			molecular function	RNA binding
Threonyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.3) (Threonine--tRNA ligase) (ThrRS) (Threonyl-tRNA synthetase-like 1). [Uniprot/SWISSPROT;Acc:Q9BW92]	2.25955	down	biological process	threonyl-tRNA aminoacylation
				translation
				tRNA aminoacylation for protein translation
			cellular component	cytoplasm
				mitochondrion
			molecular function	aminoacyl-tRNA ligase activity
				ATP binding
				ligase activity
				nucleotide binding
				threonine-tRNA ligase activity
Thrombospondin-4 precursor. [Uniprot/SWISSPROT;Acc:P35443]	3.05037		biological process	cell adhesion
				substrate-bound cell migration, cell extension
			cellular component	extracellular region
				proteinaceous extracellular matrix
			molecular function	calcium ion binding
				heparin binding
				protein binding
				structural molecule activity
Thyroglobulin precursor. [Uniprot/SWISSPROT;Acc:P01266]	1.19212		biological process	hormone biosynthetic process
				signal transduction
				thyroid hormone generation
			cellular component	extracellular region
			molecular function	hormone activity
Toll-interacting protein. [Uniprot/SWISSPROT;Acc:Q9H0E2]	3.54414	up	biological process	cell-cell signaling
				immune response
				inflammatory response
				intracellular signaling cascade
				leukocyte activation
				phosphorylation
			cellular component	cytoplasm
				interleukin-1 receptor complex
				interleukin-18 receptor complex

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.