MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	Ratio	Gene Ontology	description	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2201 to 2250 of 2667 in total

Regulation  : up

Ratio	Gene Ontology	description	Class
2.45764	cation transport	zinc transporter like 2 [RefSeq_peptide;Acc:NP_598003]	biological process
	cation transporter activity		molecular function
	cytoplasmic membrane-bound vesicle		cellular component
	Golgi apparatus
	membrane
	protein binding		molecular function
	zinc ion transport		biological process
	zinc ion transporter activity		molecular function
2.45875	extracellular matrix	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19). [Uniprot/SWISSPROT;Acc:Q8TE59]	cellular component
	intracellular
	metal ion binding		molecular function
	metalloendopeptidase activity
	metallopeptidase activity
	nucleic acid binding
	peptidase activity
	proteinaceous extracellular matrix		cellular component
	proteolysis		biological process
	zinc ion binding		molecular function
2.48474	endoplasmic reticulum	BET1 homolog (Golgi vesicular membrane-trafficking protein p18) (hBET1). [Uniprot/SWISSPROT;Acc:O15155]	cellular component
	ER to Golgi vesicle-mediated transport		biological process
	Golgi apparatus		cellular component
	Golgi membrane
	integral to membrane
	membrane
	protein binding		molecular function
	protein transport		biological process
2.49031	nervous system development	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta). [Uniprot/SWISSPROT;Acc:Q99767]
	protein binding		molecular function
	protein transport		biological process
2.4954	membrane	OMA1 homolog, zinc metallopeptidase [RefSeq_peptide;Acc:NP_660286]	cellular component
	metalloendopeptidase activity		molecular function
	metallopeptidase activity
	proteolysis		biological process
	zinc ion binding		molecular function
2.54508	cell adhesion	Neuroligin-2 precursor. [Uniprot/SWISSPROT;Acc:Q8NFZ4]	biological process
	cell-cell adhesion
	cholinesterase activity		molecular function
	integral to membrane		cellular component
	intercellular junction maintenance		biological process
	membrane		cellular component
	neurexin binding		molecular function
	postsynaptic membrane		cellular component
	synapse
	synaptogenesis		biological process
2.57202	integral to membrane	Protein GPR107 precursor (Lung seven transmembrane receptor 1). [Uniprot/SWISSPROT;Acc:Q5VW38]	cellular component
	membrane
2.65068	calcium ion binding	NULL	molecular function
	complement activation		biological process
	extracellular region		cellular component
	proteolysis		biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.