MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	description	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2190 to 2239 of 2667 in total

Ratio	Regulation	description	Class	Gene Ontology
3.31364	up	Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Diglyceride acyltransferase 2). [Uniprot/SWISSPROT;Acc:Q96PD7]	molecular function	acyltransferase activity
				diacylglycerol O-acyltransferase activity
				transferase activity
3.32356		Nuclear receptor-interacting protein 3 (Sarcoma antigen NY-SAR-105). [Uniprot/SWISSPROT;Acc:Q9NQ35]	biological process	proteolysis
			molecular function	aspartic-type endopeptidase activity
				sugar binding
3.35536		RNA polymerase-associated protein RTF1 homolog. [Uniprot/SWISSPROT;Acc:Q92541]	biological process	regulation of transcription, DNA-dependent
				transcription
			cellular component	nucleolus
				nucleus
			molecular function	calmodulin binding
3.36725		TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein). [Uniprot/SWISSPROT;Acc:Q15633]	biological process	negative regulation of antiviral response by host
				negative regulation of protein kinase activity
				positive regulation of viral genome replication
				positive regulation of viral protein levels in host cell
				regulation of transcription from RNA polymerase II promoter
				regulation of viral transcription
			cellular component	intracellular
				nucleus
			molecular function	double-stranded RNA binding
				protein binding
				protein heterodimerization activity
3.39764	down	Junctophilin-1 (Junctophilin type 1) (JP-1). [Uniprot/SWISSPROT;Acc:Q9HDC5]	biological process	biological_process
				muscle development
			cellular component	integral to membrane
				junctional membrane complex
				membrane
				microsome
				sarcoplasmic reticulum
				Z disc
			molecular function	molecular_function
				structural constituent of muscle
3.41415	up	Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamma-7 subunit). [Uniprot/SWISSPROT;Acc:P62955]	biological process	calcium ion transport
				ion transport
			cellular component	integral to membrane
				membrane
				voltage-gated calcium channel complex
			molecular function	calcium ion binding
				voltage-gated calcium channel activity
				voltage-gated ion channel activity
3.41794		LRRC44 protein. [Uniprot/SPTREMBL;Acc:Q6P5P7]		protein binding
3.43019	down	Pre-mRNA-splicing factor SYF2 (CCNDBP1-interactor) (p29). [Uniprot/SWISSPROT;Acc:O95926]	biological process	biological_process
				mRNA processing
				RNA splicing
			cellular component	nucleus
				spliceosome
			molecular function	protein binding
3.48313		Homeobox protein TGIF2 (5'-TG-3'-interacting factor 2) (TGFB-induced factor 2) (TGF(beta)-induced transcription factor 2). [Uniprot/SWISSPROT;Acc:Q9GZN2]	biological process	regulation of transcription, DNA-dependent
			cellular component	nucleus
			molecular function	sequence-specific DNA binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.