MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Regulation	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2101 to 2150 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
Signal peptidase complex catalytic subunit SEC11C (EC 3.4.-.-) (SEC11 homolog C) (SEC11-like protein 3) (Microsomal signal peptidase 21 kDa subunit) (SPase 21 kDa subunit) (SPC21). [Uniprot/SWISSPROT;Acc:Q9BY50]	1.96673	up	endoplasmic reticulum	cellular component
			integral to membrane
			membrane
			microsome
			peptidase activity	molecular function
			proteolysis	biological process
			serine-type peptidase activity	molecular function
			signal peptide processing	biological process
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14). [Uniprot/SWISSPROT;Acc:Q9UN76]	1.40552	down	amino acid metabolic process
			amino acid transport
			amino acid transporter activity	molecular function
			dicarboxylic acid transport	biological process
			integral to plasma membrane	cellular component
			membrane
			neurotransmitter transport	biological process
			neurotransmitter:sodium symporter activity	molecular function
			sodium:dicarboxylate symporter activity
			symporter activity
Sodium- and chloride-dependent transporter XTRP3 (Solute carrier family 6 member 20) (Neurotransmitter transporter rB21A homolog). [Uniprot/SWISSPROT;Acc:Q9NP91]	1.11083		integral to plasma membrane	cellular component
			membrane
			neurotransmitter transport	biological process
			neurotransmitter:sodium symporter activity	molecular function
			plasma membrane	cellular component
			symporter activity	molecular function
			transporter activity
Sodium-dependent serotonin transporter (5HT transporter) (5HTT). [Uniprot/SWISSPROT;Acc:P31645]	1.42215		integral to plasma membrane	cellular component
			membrane
			monoamine transport	biological process
			monoamine transporter activity	molecular function
			neurotransmitter transport	biological process
			neurotransmitter uptake
			neurotransmitter:sodium symporter activity	molecular function
			protein binding
			serotonin transport	biological process
			serotonin transporter activity	molecular function
			serotonin:sodium symporter activity
			symporter activity
Sodium/potassium-transporting ATPase subunit alpha-4 (EC 3.6.3.9) (Sodium pump subunit alpha-4) (Na(+)/K(+) ATPase alpha-4 subunit). [Uniprot/SWISSPROT;Acc:Q13733]	1.20619		ATP binding
			ATP hydrolysis coupled proton transport	biological process
			ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	molecular function
			catalytic activity
			cation transport	biological process
			GABA-B receptor activity	molecular function
			hydrogen ion homeostasis	biological process
			hydrolase activity	molecular function
			hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
			integral to membrane	cellular component
			magnesium ion binding	molecular function
			membrane	cellular component
			metabolic process	biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.