MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene Ontology	Regulation	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 201 to 250 of 2667 in total

description	Ratio	Gene Ontology	Regulation	Class
Autophagy-related protein 10 (APG10-like). [Uniprot/SWISSPROT;Acc:Q9H0Y0]	1.28319	cytoplasm	up	cellular component
		intracellular
		positive regulation of protein modification		biological process
		protein amino acid lipidation
		protein binding		molecular function
		protein transport		biological process
		ubiquitin cycle
Bardet-Biedl syndrome 5 protein. [Uniprot/SWISSPROT;Acc:Q8N3I7]	1.34491	cellular_component		cellular component
		cilium
		intracellular
		molecular_function		molecular function
		response to stimulus		biological process
		visual perception
Bcl-2-interacting killer (Apoptosis inducer NBK) (BP4) (BIP1). [Uniprot/SWISSPROT;Acc:Q13323]	1.21871	apoptotic program	down
		induction of apoptosis
		integral to membrane		cellular component
		membrane
		mitochondrial envelope
		protein binding		molecular function
		regulation of apoptosis		biological process
BET1 homolog (Golgi vesicular membrane-trafficking protein p18) (hBET1). [Uniprot/SWISSPROT;Acc:O15155]	2.48474	endoplasmic reticulum	up	cellular component
		ER to Golgi vesicle-mediated transport		biological process
		Golgi apparatus		cellular component
		Golgi membrane
		integral to membrane
		membrane
		protein binding		molecular function
		protein transport		biological process
Beta-defensin 2 precursor (BD-2) (hBD-2) (Defensin, beta 2) (Skin- antimicrobial peptide 1) (SAP1). [Uniprot/SWISSPROT;Acc:O15263]	1.51342	chemotaxis	down
		defense response
		defense response to bacterium
		extracellular region		cellular component
		G-protein coupled receptor protein signaling pathway		biological process
		immune response
Beta-mannosidase precursor (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase). [Uniprot/SWISSPROT;Acc:O00462]	1.33329	beta-mannosidase activity	up	molecular function
		carbohydrate metabolic process		biological process
		cation binding		molecular function
		glycoprotein catabolic process		biological process
		hydrolase activity, hydrolyzing O-glycosyl compounds		molecular function
		lysosome		cellular component
		metabolic process		biological process
		protein modification process
Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Uniprot/SWISSPROT;Acc:P12643]	1.49558	BMP signaling pathway	down
		bone mineralization
		cardiac cell differentiation
		cartilage development
		cell fate commitment
		cell growth
		cell-cell signaling
		cytokine activity		molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.