MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1901 to 1950 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon). [Uniprot/SWISSPROT;Acc:P23469]	4.03725	up	biological process	protein amino acid dephosphorylation
				transmembrane receptor protein tyrosine phosphatase signaling pathway
			cellular component	cytoplasm
				integral to plasma membrane
				membrane
				soluble fraction
			molecular function	hydrolase activity
				phosphoric monoester hydrolase activity
				protein homodimerization activity
				protein tyrosine phosphatase activity
				receptor activity
				transmembrane receptor protein tyrosine phosphatase activity
Rho GTPase-activating protein 24 (Rho-type GTPase-activating protein 24) (Filamin-A-associated RhoGAP) (FilGAP) (p73RhoGAP) (RhoGAP of 73 kDa) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Sarcoma antigen NY-SAR-88). [Uniprot/SWISSPROT;Acc:Q8N264]	1.36997		biological process	angiogenesis
				cell differentiation
				multicellular organismal development
				signal transduction
			cellular component	cell junction
				cytoplasm
				cytoskeleton
				intracellular
				membrane
			molecular function	GTPase activator activity
				protein binding
Rho-related BTB domain-containing protein 1. [Uniprot/SWISSPROT;Acc:O94844]	5.31521		biological process	protein transport
				small GTPase mediated signal transduction
			cellular component	intracellular
			molecular function	GTP binding
				nucleotide binding
				protein binding
Rhophilin-1 (GTP-Rho-binding protein 1). [Uniprot/SWISSPROT;Acc:Q8TCX5]	1.80858	down	biological process	signal transduction
			cellular component	intracellular
			molecular function	protein binding
				small GTPase regulator activity
Ribonuclease P protein subunit p29 (EC 3.1.26.5) (hPOP4). [Uniprot/SWISSPROT;Acc:O95707]	2.12709		biological process	rRNA processing
				tRNA processing
			cellular component	nucleus
				ribonuclease MRP complex
				ribonuclease P complex
			molecular function	hydrolase activity
				identical protein binding
				ribonuclease activity
				ribonuclease P activity
				RNA binding
RIM-binding protein 2 (RIM-BP2). [Uniprot/SWISSPROT;Acc:O15034]	2.27115		cellular component	cell junction
				membrane
				synapse
RING finger protein 170 (Putative LAG1-interacting protein). [Uniprot/SWISSPROT;Acc:Q96K19]	5.61927		biological process	transport
			cellular component	integral to membrane
				membrane
			molecular function	metal ion binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.