MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Regulation	Ratio	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1901 to 1950 of 2667 in total

description	Regulation	Ratio	Gene Ontology	Class
Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon). [Uniprot/SWISSPROT;Acc:P23469]	up	4.03725	dephosphorylation	biological process
			hydrolase activity	molecular function
			integral to plasma membrane	cellular component
			membrane
			phosphoric monoester hydrolase activity	molecular function
			protein amino acid dephosphorylation	biological process
			protein homodimerization activity	molecular function
			protein tyrosine phosphatase activity
			receptor activity
			soluble fraction	cellular component
			transmembrane receptor protein tyrosine phosphatase activity	molecular function
			transmembrane receptor protein tyrosine phosphatase signaling pathway	biological process
Rho GTPase-activating protein 24 (Rho-type GTPase-activating protein 24) (Filamin-A-associated RhoGAP) (FilGAP) (p73RhoGAP) (RhoGAP of 73 kDa) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Sarcoma antigen NY-SAR-88). [Uniprot/SWISSPROT;Acc:Q8N264]		1.36997	angiogenesis
			cell differentiation
			cell junction	cellular component
			cytoplasm
			cytoskeleton
			GTPase activator activity	molecular function
			intracellular	cellular component
			membrane
			multicellular organismal development	biological process
			protein binding	molecular function
			signal transduction	biological process
Rho-related BTB domain-containing protein 1. [Uniprot/SWISSPROT;Acc:O94844]		5.31521	GTP binding	molecular function
			intracellular	cellular component
			nucleotide binding	molecular function
			protein binding
			protein transport	biological process
			small GTPase mediated signal transduction
Rhophilin-1 (GTP-Rho-binding protein 1). [Uniprot/SWISSPROT;Acc:Q8TCX5]	down	1.80858	intracellular	cellular component
			protein binding	molecular function
			signal transduction	biological process
			small GTPase regulator activity	molecular function
Ribonuclease P protein subunit p29 (EC 3.1.26.5) (hPOP4). [Uniprot/SWISSPROT;Acc:O95707]		2.12709	hydrolase activity
			identical protein binding
			nucleus	cellular component
			ribonuclease activity	molecular function
			ribonuclease MRP complex	cellular component
			ribonuclease P activity	molecular function
			ribonuclease P complex	cellular component
			RNA binding	molecular function
			rRNA processing	biological process
			tRNA processing
RIM-binding protein 2 (RIM-BP2). [Uniprot/SWISSPROT;Acc:O15034]		2.27115	cell junction	cellular component
			membrane
			synapse
RING finger protein 170 (Putative LAG1-interacting protein). [Uniprot/SWISSPROT;Acc:Q96K19]		5.61927	integral to membrane
			membrane
			metal ion binding	molecular function
			nucleoside transporter activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.