MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Regulation	Ratio	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1851 to 1900 of 2667 in total

description	Regulation	Ratio	Gene Ontology	Class
rab and DnaJ domain containing [RefSeq_peptide;Acc:NP_057628]	up	5.53059	protein transport	biological process
			signal transduction
			small GTPase mediated signal transduction
Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). [Uniprot/SWISSPROT;Acc:Q13905]	down	1.49923	blood vessel development
			cell-cell adhesion
			guanyl-nucleotide exchange factor activity	molecular function
			intracellular	cellular component
			platelet-derived growth factor receptor signaling pathway	biological process
			protein binding	molecular function
			regulation of small GTPase mediated signal transduction	biological process
			signal transduction
			small GTPase mediated signal transduction
			transmembrane receptor protein tyrosine kinase signaling pathway
RAS-like, family 11, member A [RefSeq_peptide;Acc:NP_996563]	up	1.7961	GTP binding	molecular function
			intracellular	cellular component
			nucleotide binding	molecular function
			protein transport	biological process
			small GTPase mediated signal transduction
Ras-related GTP-binding protein D (Rag D). [Uniprot/SWISSPROT;Acc:Q9NQL2]		1.19117	cytoplasm	cellular component
			G-protein coupled receptor protein signaling pathway	biological process
			GTP binding	molecular function
			guanyl nucleotide binding
			nucleotide binding
			nucleus	cellular component
			protein binding	molecular function
			signal transducer activity
			transport	biological process
Ras-related protein Rab-17. [Uniprot/SWISSPROT;Acc:Q9H0T7]		1.95876	GTP binding	molecular function
			GTPase activity
			intracellular	cellular component
			intracellular protein transport	biological process
			nucleocytoplasmic transport
			nucleotide binding	molecular function
			protein binding
			protein transport	biological process
			signal transduction
			small GTPase mediated signal transduction
Ras-related protein Rab-36. [Uniprot/SWISSPROT;Acc:O95755]		1.89308	Golgi apparatus	cellular component
			GTP binding	molecular function
			GTPase activity
			intracellular	cellular component
			intracellular protein transport	biological process
			membrane	cellular component
			nucleocytoplasmic transport	biological process
			nucleotide binding	molecular function
			protein binding
			protein transport	biological process
			signal transduction
			small GTPase mediated signal transduction
Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon). [Uniprot/SWISSPROT;Acc:P23469]		4.03725	cytoplasm	cellular component

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.