MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	description	Gene Ontology	Class	Gene	Accession	Maximum Ratio	Minimum Ratio

Results: HTML CSV LaTeX

Showing element 1751 to 1800 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
2.10428	up	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39). [Uniprot/SWISSPROT;Acc:P05412]	negative regulation of protein amino acid autophosphorylation	biological process
			nuclear chromosome	cellular component
			nucleus
			positive regulation of transcription from RNA polymerase II promoter	biological process
			protein dimerization activity	molecular function
			regulation of progression through cell cycle	biological process
			regulation of transcription
			regulation of transcription, DNA-dependent
			RNA polymerase II transcription factor activity	molecular function
			sequence-specific DNA binding
			transcription factor activity
			transcription factor complex	cellular component
2.11557	down	Echinoderm microtubule-associated protein-like 5 (EMAP-5). [Uniprot/SWISSPROT;Acc:Q05BV3]	cytoplasm
			microtubule
2.12709		Ribonuclease P protein subunit p29 (EC 3.1.26.5) (hPOP4). [Uniprot/SWISSPROT;Acc:O95707]	hydrolase activity	molecular function
			identical protein binding
			nucleus	cellular component
			ribonuclease activity	molecular function
			ribonuclease MRP complex	cellular component
			ribonuclease P activity	molecular function
			ribonuclease P complex	cellular component
			RNA binding	molecular function
			rRNA processing	biological process
			tRNA processing
2.16131		39S ribosomal protein L15, mitochondrial precursor (L15mt) (MRP-L15). [Uniprot/SWISSPROT;Acc:Q9P015]	intracellular	cellular component
			large ribosomal subunit
			mitochondrion
			ribosome
			structural constituent of ribosome	molecular function
			translation	biological process
2.20843	up	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes). [Uniprot/SWISSPROT;Acc:P07947]	ATP binding	molecular function
			cytoplasm	cellular component
			glucose transport	biological process
			intracellular signaling cascade
			membrane fraction	cellular component
			nucleotide binding	molecular function
			protein amino acid autophosphorylation	biological process
			protein amino acid phosphorylation
			protein binding	molecular function
			protein kinase activity
			protein modification process	biological process
			protein serine/threonine kinase activity	molecular function
			protein-tyrosine kinase activity
			transferase activity
2.25955	down	Threonyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.3) (Threonine--tRNA ligase) (ThrRS) (Threonyl-tRNA synthetase-like 1). [Uniprot/SWISSPROT;Acc:Q9BW92]	aminoacyl-tRNA ligase activity
			ATP binding
			cytoplasm	cellular component
			ligase activity	molecular function
			mitochondrion	cellular component
			nucleotide binding	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.