MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Regulation	Gene	Gene Ontology	Accession	Class	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1551 to 1600 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1). [Uniprot/SWISSPROT;Acc:Q9H4M7]	1.17693	up	phosphatidylinositol binding	molecular function
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta). [Uniprot/SWISSPROT;Acc:Q86SQ0]	1.5415	down	chloride transport	biological process
			cytoplasm	cellular component
			intracellular signaling cascade	biological process
			membrane	cellular component
			phospholipase C activity	molecular function
			signal transduction	biological process
			voltage-gated chloride channel activity	molecular function
Podocalyxin-like protein 2 precursor (Endoglycan). [Uniprot/SWISSPROT;Acc:Q9NZ53]	1.15279	up	cell adhesion	biological process
			glycosaminoglycan binding	molecular function
			integral to plasma membrane	cellular component
			membrane
			protein binding	molecular function
			structural molecule activity
			viral capsid	cellular component
Poliovirus receptor-related protein 3 precursor (Nectin-3) (CD113 antigen) (CDw113). [Uniprot/SWISSPROT;Acc:Q9NQS3]	1.4628		apical junction complex
			cell adhesion	biological process
			cell-cell adherens junction	cellular component
			homophilic cell adhesion	biological process
			integral to membrane	cellular component
			plasma membrane
			protein binding	molecular function
			protein homodimerization activity
			receptor activity
Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3). [Uniprot/SWISSPROT;Acc:P22001]	4.67988		delayed rectifier potassium channel activity
			dicarboxylic acid transport	biological process
			integral to membrane	cellular component
			ion channel activity	molecular function
			ion transport	biological process
			membrane	cellular component
			membrane fraction
			outward rectifier potassium channel activity	molecular function
			potassium ion binding
			potassium ion transport	biological process
			protein binding	molecular function
			sodium:dicarboxylate symporter activity
			voltage-gated ion channel activity
			voltage-gated potassium channel activity
			voltage-gated potassium channel complex	cellular component
Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4). [Uniprot/SWISSPROT;Acc:P56696]	1.17879		inner ear morphogenesis	biological process
			ion channel activity	molecular function
			ion transport	biological process
			membrane	cellular component
			membrane fraction
			potassium ion binding	molecular function
			potassium ion transport	biological process
			sensory perception of sound
			voltage-gated ion channel activity	molecular function
			voltage-gated potassium channel activity
			voltage-gated potassium channel complex	cellular component

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.