MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	Ratio	description	Class	Gene Ontology	Gene	Minimum Ratio	Maximum Ratio	Accession

Results: HTML CSV LaTeX

Showing element 1501 to 1550 of 2667 in total

Regulation  : up

Ratio	description	Class	Gene Ontology
1.25808	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Uniprot/SWISSPROT;Acc:Q9P2D1]	biological process	camera-type eye development
			chromatin assembly or disassembly
			chromatin modification
			circulation
			embryonic hindlimb morphogenesis
			female genitalia development
			heart morphogenesis
			in utero embryonic development
			inner ear morphogenesis
			locomotory behavior
			nose development
			palate development
			positive regulation of body size
			regulation of transcription, DNA-dependent
			sensory perception of sound
			transcription
		cellular component	chromatin
			nucleus
		molecular function	ATP binding
			chromatin binding
			DNA binding
			helicase activity
			hydrolase activity
			nucleic acid binding
			nucleotide binding
1.2734	Neurexin-2-alpha precursor (Neurexin II-alpha). [Uniprot/SWISSPROT;Acc:Q9P2S2]	biological process	cell adhesion
			neurotransmitter secretion
			synaptic transmission
			synaptogenesis
		cellular component	integral to membrane
			membrane
		molecular function	calcium channel regulator activity
			calcium ion binding
			protein binding
1.27516	Uncharacterized protein C16orf48. [Uniprot/SWISSPROT;Acc:Q9H0I2]	cellular component	microtubule cytoskeleton
1.28319	Autophagy-related protein 10 (APG10-like). [Uniprot/SWISSPROT;Acc:Q9H0Y0]	biological process	autophagy
			positive regulation of protein modification
			protein amino acid lipidation
			protein transport
			ubiquitin cycle
		cellular component	cytoplasm
			intracellular
		molecular function	protein binding
1.28514	EF-hand domain-containing protein C17orf57. [Uniprot/SWISSPROT;Acc:Q8IY85]		calcium ion binding
1.28698	THO complex subunit 2 (Tho2). [Uniprot/SWISSPROT;Acc:Q8NI27]	biological process	mRNA processing
			mRNA transport
			RNA splicing
			transport
		cellular component	nucleus
		molecular function	RNA binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.