MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Class	Ratio	Regulation	description	Gene Ontology	Gene	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 151 to 200 of 2667 in total

Class  : biological process

Ratio	Regulation	description	Gene Ontology
1.21871	down	Bcl-2-interacting killer (Apoptosis inducer NBK) (BP4) (BIP1). [Uniprot/SWISSPROT;Acc:Q13323]	regulation of apoptosis
1.22047	up	HORMA domain-containing protein 1 (Newborn ovary HORMA protein) (Cancer/testis antigen CT46). [Uniprot/SWISSPROT;Acc:Q86X24]	mitosis
1.22178		Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22). [Uniprot/SWISSPROT;Acc:O94921]	protein amino acid phosphorylation
1.22502		ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter). [Uniprot/SWISSPROT;Acc:Q99758]	response to drug
			transport
1.22528		protein tyrosine phosphatase domain containing 1 protein isoform 2 [RefSeq_peptide;Acc:NP_818931]	dephosphorylation
			protein amino acid dephosphorylation
1.22576		Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1). [Uniprot/SWISSPROT;Acc:Q9UIS9]	negative regulation of transcription
			regulation of transcription, DNA-dependent
			transcription
			transcription from RNA polymerase II promoter
1.22694		Protein FAM73B. [Uniprot/SPTREMBL;Acc:Q7L4E1]	type I hypersensitivity
1.23668	down	Myosin-If (Myosin-Ie). [Uniprot/SWISSPROT;Acc:O00160]	biological_process
1.23783		Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein). [Uniprot/SWISSPROT;Acc:Q8WZ64]	regulation of GTPase activity
			signal transduction
1.23845		Insulin-induced gene 1 protein (INSIG-1). [Uniprot/SWISSPROT;Acc:O15503]	cell proliferation
			cholesterol metabolic process
			lipid metabolic process
			metabolic process
			response to sterol depletion
			steroid metabolic process
1.24114		Myosin-15 (Myosin heavy chain 15). [Uniprot/SWISSPROT;Acc:Q9Y2K3]	signal transduction
			striated muscle contraction
1.24359		Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2). [Uniprot/SWISSPROT;Acc:Q86UW7]	exocytosis
			protein transport
1.24361		Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase). [Uniprot/SWISSPROT;Acc:P33908]	metabolic process
			protein amino acid glycosylation
1.24964		Atlastin-2 (ADP-ribosylation factor-like protein 6-interacting protein 2). [Uniprot/SWISSPROT;Acc:Q8NHH9]	immune response
1.25113		Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146). [Uniprot/SWISSPROT;Acc:Q15072]	regulation of transcription, DNA-dependent
1.25147	up	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63). [Uniprot/SWISSPROT;Acc:P42081]	cell-cell signaling
			immune response
			positive regulation of cell proliferation
			positive regulation of interleukin-2 biosynthetic process
			positive regulation of interleukin-4 biosynthetic process
			positive regulation of lymphotoxin A biosynthetic process
			positive regulation of T-helper 2 cell differentiation
			positive regulation of transcription
			T cell activation
			T cell proliferation
1.25205	down	Protein CWC15 homolog. [Uniprot/SWISSPROT;Acc:Q9P013]	nuclear mRNA splicing, via spliceosome
			RNA splicing
			SRP-dependent cotranslational protein targeting to membrane
1.25729	up	Dehydrogenase/reductase SDR family member 1 (EC 1.1.-.-). [Uniprot/SWISSPROT;Acc:Q96LJ7]	enterobactin biosynthetic process
			metabolic process
1.25808		Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Uniprot/SWISSPROT;Acc:Q9P2D1]	adult heart development
			adult walking behavior
			blood vessel development
			camera-type eye development
			chromatin assembly or disassembly
			chromatin modification

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.