MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene Ontology	Class	Regulation	Gene	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1393 to 1442 of 2667 in total

description	Ratio	Gene Ontology	Class	Regulation
Nuclear RNA export factor 2 (TAP-like protein 2) (TAPL-2). [Uniprot/SWISSPROT;Acc:Q9GZY0]	1.19207	intracellular	cellular component	up
		mRNA export from nucleus	biological process
		multicellular organismal development
		nuclear RNA export factor complex	cellular component
		nucleotide binding	molecular function
		nucleus	cellular component
		protein binding	molecular function
		RNA binding
		transport	biological process
nucleolar and spindle associated protein 1 isoform 2 [RefSeq_peptide;Acc:NP_060924]	1.2984	cytokinesis after mitosis		down
		establishment of mitotic spindle localization
		microtubule binding	molecular function
		mitotic chromosome condensation	biological process
		nucleolus	cellular component
		positive regulation of mitosis	biological process
		spindle microtubule	cellular component
Nucleolar preribosomal-associated protein 1 (Fragment). [Uniprot/SWISSPROT;Acc:O60287]	1.36755	biological_process	biological process
		molecular_function	molecular function
		nucleolus	cellular component
		nucleus
Nucleoplasmin-2. [Uniprot/SWISSPROT;Acc:Q86SE8]	5.83544	chromatin remodeling	biological process
		cytoplasmic chromatin	cellular component
		embryonic development	biological process
		histone binding	molecular function
		nuclear chromatin	cellular component
		nucleic acid binding	molecular function
		nucleus	cellular component
		oocyte differentiation	biological process
		positive regulation of meiosis
		regulation of exit from mitosis
		single fertilization
NULL	1.18711	protein binding	molecular function	up
	1.37553	peptidyl-prolyl cis-trans isomerase activity
		protein folding	biological process
	1.40093	protein binding	molecular function
	1.45314	DNA binding
	2.65068	calcium ion binding
		complement activation	biological process
		extracellular region	cellular component
		proteolysis	biological process
		serine-type endopeptidase activity	molecular function
olfactomedin-like 2A [RefSeq_peptide;Acc:NP_872293]	3.66058	extracellular matrix	cellular component	down
		extracellular matrix binding	molecular function
		latrotoxin receptor activity
		membrane	cellular component
		protein homodimerization activity	molecular function
Olfactory receptor 1J2 (Olfactory receptor OR9-19) (OST044) (HSA5) (HTPCRX15). [Uniprot/SWISSPROT;Acc:Q8NGS2]	2.86538	cannabinoid receptor activity		up
		G-protein coupled receptor protein signaling pathway	biological process
		integral to membrane	cellular component
		olfactory receptor activity	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.