MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene Ontology	Regulation	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1301 to 1350 of 2667 in total

description	Ratio	Gene Ontology	Regulation	Class
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)]. [Uniprot/SWISSPROT;Acc:O15527]	1.35022	protein binding	up	molecular function
Nck-associated protein 1-like (Membrane-associated protein HEM-1) (Hematopoietic protein 1). [Uniprot/SWISSPROT;Acc:P55160]	1.47697	integral to plasma membrane		cellular component
		membrane
		membrane fraction
NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein). [Uniprot/SWISSPROT;Acc:Q86UW6]	3.21581	ATP binding		molecular function
		ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
		cytoplasm		cellular component
		endonuclease activity		molecular function
		hydrolase activity
		nucleotide binding
		protein binding
Neurexin-2-alpha precursor (Neurexin II-alpha). [Uniprot/SWISSPROT;Acc:Q9P2S2]	1.2734	calcium channel regulator activity
		calcium ion binding
		cell adhesion		biological process
		integral to membrane		cellular component
		membrane
		neurotransmitter secretion		biological process
		protein binding		molecular function
		synaptic transmission		biological process
		synaptogenesis
Neuroligin-2 precursor. [Uniprot/SWISSPROT;Acc:Q8NFZ4]	2.54508	cell adhesion
		cell-cell adhesion
		cholinesterase activity		molecular function
		integral to membrane		cellular component
		intercellular junction maintenance		biological process
		membrane		cellular component
		neurexin binding		molecular function
		postsynaptic membrane		cellular component
		synapse
		synaptogenesis		biological process
Neurosecretory protein VGF precursor. [Uniprot/SWISSPROT;Acc:O15240]	1.20481	biological_process	down
		cellular_component		cellular component
		cytoplasmic vesicle
		generation of precursor metabolites and energy		biological process
		growth factor activity		molecular function
		neuropeptide hormone activity
		ovarian follicle development		biological process
		sexual reproduction
Ninein-like protein. [Uniprot/SWISSPROT;Acc:Q9Y2I6]	3.15011	calcium ion binding		molecular function
		cytoplasm		cellular component
		microtubule
Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Uniprot/SWISSPROT;Acc:Q12968]	5.32612	cellular respiration		biological process
		cytoplasm		cellular component
		heart development		biological process
		inflammatory response
		nucleus		cellular component
		protein binding		molecular function
		regulation of transcription		biological process
		regulation of transcription from RNA polymerase II promoter
		regulation of transcription, DNA-dependent

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.