MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	description	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1301 to 1350 of 2667 in total

Ratio	Regulation	description	Class	Gene Ontology
1.59819	up	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2). [Uniprot/SWISSPROT;Acc:O14830]	biological process	detection of stimulus during sensory perception
				protein amino acid dephosphorylation
				response to stimulus
				visual perception
			molecular function	calcium ion binding
				hydrolase activity
				iron ion binding
				manganese ion binding
				phosphoprotein phosphatase activity
				protein serine/threonine phosphatase activity
1.60668		Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC [Uniprot/SWISSPROT;Acc:Q9HBA0]	biological process	calcium ion homeostasis
				calcium ion transport
				ion transport
				osmosensory signaling pathway
				regulation of cell volume
				response to mechanical stimulus
			cellular component	integral to membrane
				membrane
				plasma membrane
			molecular function	calcium channel activity
				calcium ion binding
				calmodulin binding
				identical protein binding
				ion channel activity
1.60746	down	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Uniprot/SWISSPROT;Acc:Q8TD26]	biological process	chromatin assembly or disassembly
				chromatin remodeling
				nervous system development
				nucleosome assembly
				regulation of transcription, DNA-dependent
				response to antibiotic
				tetracycline transport
				transcription
			cellular component	chromatin
				integral to membrane
				nucleosome
				nucleus
			molecular function	ATP binding
				ATP-dependent helicase activity
				chromatin binding
				DNA binding
				helicase activity
				hydrolase activity
				nucleic acid binding
				nucleotide binding
				tetracycline:hydrogen antiporter activity
1.61347		Calmodulin-like protein 5 (Calmodulin-like skin protein). [Uniprot/SWISSPROT;Acc:Q9NZT1]	biological process	ciliary or flagellar motility
				epidermis development
				signal transduction
			cellular component	flagellin-based flagellum
			molecular function	calcium ion binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.