MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	description	Gene Ontology	Gene	Class	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1243 to 1292 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
1.54317	up	Dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) (DolP- glucosyltransferase). [Uniprot/SWISSPROT;Acc:Q9Y673]	transferase activity, transferring glycosyl groups	molecular function
1.54676	down	WAS protein homology region 2 domain containing 1 [RefSeq_peptide;Acc:NP_001073904]	actin binding
			actin cytoskeleton	cellular component
			cell adhesion	biological process
			extracellular region	cellular component
			hormone activity	molecular function
			structural molecule activity
1.55809		Phosphatidylinositol N-acetylglucosaminyltransferase subunit H (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class H protein) (PIG-H). [Uniprot/SWISSPROT;Acc:Q14442]	cytoplasm	cellular component
			endoplasmic reticulum
			GPI anchor biosynthetic process	biological process
			phosphatidylinositol N-acetylglucosaminyltransferase activity	molecular function
			protein modification process	biological process
			transferase activity, transferring glycosyl groups	molecular function
1.55844	up	TP53-target gene 5 protein (TP53-inducible gene 5 protein). [Uniprot/SWISSPROT;Acc:Q9Y2B4]	intracellular signaling cascade	biological process
			molecular_function	molecular function
			negative regulation of cell growth	biological process
1.56335		Zinc finger SWIM domain-containing protein 3. [Uniprot/SWISSPROT;Acc:Q96MP5]	metal ion binding	molecular function
			zinc ion binding
1.57088		Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein). [Uniprot/SWISSPROT;Acc:O15409]	caudate nucleus development	biological process
			intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			protein homodimerization activity	molecular function
			putamen development	biological process
			regulation of transcription, DNA-dependent
			sequence-specific DNA binding	molecular function
			transcription	biological process
			transcription factor activity	molecular function
			zinc ion binding
1.58045	down	Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3). [Uniprot/SWISSPROT;Acc:P56589]	integral to peroxisomal membrane	cellular component
			integral to plasma membrane
			membrane
			peroxisomal membrane
			peroxisome
			peroxisome organization and biogenesis	biological process
			protein binding	molecular function
1.58115	up	Tetratricopeptide repeat protein 18 (TPR repeat protein 18). [Uniprot/SWISSPROT;Acc:Q5T0N1]	binding
1.59177		Transgelin-2 (SM22-alpha homolog). [Uniprot/SWISSPROT;Acc:P37802]	actin binding
			actomyosin structure organization and biogenesis	biological process
			muscle development
			protein binding	molecular function
1.59188		Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Trinucleotide repeat-containing gene 1 protein). [Uniprot/SWISSPROT;Acc:Q8TF68]	DNA binding
			intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription
			zinc ion binding	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.