MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	description	Ratio	Class	Gene Ontology	Gene	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1143 to 1192 of 2667 in total

Regulation	description	Ratio	Class	Gene Ontology
down	Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Uniprot/SWISSPROT;Acc:O95125]	1.89168	cellular component	intracellular
				nucleus
			molecular function	DNA binding
				metal ion binding
				nucleic acid binding
				specific RNA polymerase II transcription factor activity
				transcription factor activity
				zinc ion binding
	Zinc finger protein basonuclin-2. [Uniprot/SWISSPROT;Acc:Q6ZN30]	1.1243	biological process	regulation of transcription, DNA-dependent
				transcription
			cellular component	intracellular
				nucleus
			molecular function	DNA binding
				metal ion binding
				nucleic acid binding
				zinc ion binding
	Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146). [Uniprot/SWISSPROT;Acc:Q15072]	1.25113	biological process	regulation of transcription, DNA-dependent
			cellular component	intracellular
				nucleus
			molecular function	DNA binding
				heparin binding
				metal ion binding
				nucleic acid binding
				zinc ion binding
up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Uniprot/SWISSPROT;Acc:Q9P0K1]	1.16499	biological process	cell adhesion
				central nervous system development
				negative regulation of cell adhesion
				proteolysis
			cellular component	integral to membrane
				membrane
			molecular function	integrin binding
				metalloendopeptidase activity
				protein binding
				zinc ion binding
	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19). [Uniprot/SWISSPROT;Acc:Q8TE59]	2.45875	biological process	proteolysis
			cellular component	extracellular matrix
				intracellular
				proteinaceous extracellular matrix
			molecular function	metal ion binding
				metalloendopeptidase activity
				metallopeptidase activity
				nucleic acid binding
				peptidase activity
				zinc ion binding
	Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Uniprot/SWISSPROT;Acc:Q96A54]	5.19755	biological process	fatty acid oxidation
				hormone-mediated signaling
				lipid metabolic process
			cellular component	integral to membrane
				membrane
			molecular function	hormone binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.