MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Regulation	Ratio	Class	Accession	Gene	Gene Ontology	Maximum Ratio	Minimum Ratio

Results: HTML CSV LaTeX

Showing element 1093 to 1142 of 2667 in total

description	Regulation	Ratio	Class	Gene Ontology
Junctophilin-1 (Junctophilin type 1) (JP-1). [Uniprot/SWISSPROT;Acc:Q9HDC5]	down	3.39764	biological process	biological_process
				muscle development
			cellular component	integral to membrane
				junctional membrane complex
				membrane
				microsome
				sarcoplasmic reticulum
				Z disc
			molecular function	molecular_function
				structural constituent of muscle
Kelch-like protein 34. [Uniprot/SWISSPROT;Acc:Q8N239]	up	1.21698	biological process	electron transport
				metabolic process
			molecular function	oxidoreductase activity
				protein binding
Keratin-associated protein 19-2. [Uniprot/SWISSPROT;Acc:Q3LHN2]	down	1.69153	cellular component	intermediate filament
Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein). [Uniprot/SWISSPROT;Acc:Q9HA64]		1.18141	molecular function	kinase activity
				transferase activity
KRAB-A domain containing 1 (KRBA1), mRNA [RefSeq_dna;Acc:NM_032534]	up	1.66123	biological process	G-protein coupled receptor protein signaling pathway
				regulation of transcription, DNA-dependent
			cellular component	intracellular
				membrane
			molecular function	muscarinic acetylcholine receptor activity
				nucleic acid binding
Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor). [Uniprot/SWISSPROT;Acc:Q96MU8]		3.89584	biological process	cell communication
				Wnt receptor signaling pathway
			cellular component	integral to membrane
				membrane
				membrane fraction
			molecular function	molecular_function
LAG1 longevity assurance homolog 4. [Uniprot/SWISSPROT;Acc:Q9HA82]		1.50206	biological process	ceramide biosynthetic process
				lipid biosynthetic process
				regulation of transcription, DNA-dependent
			cellular component	endoplasmic reticulum
				integral to membrane
				membrane
				nucleus
			molecular function	sequence-specific DNA binding
				transcription factor activity
Lariat debranching enzyme (EC 3.1.-.-). [Uniprot/SWISSPROT;Acc:Q9UK59]		1.37411	biological process	mRNA processing
				nuclear mRNA splicing, via spliceosome
				RNA splicing, via transesterification reactions
			cellular component	nucleus
			molecular function	hydrolase activity
				hydrolase activity, acting on ester bonds
				metal ion binding
				RNA lariat debranching enzyme activity
leucine-rich repeat neuronal 6A [RefSeq_peptide;Acc:NP_116197]	down	2.79087	biological process	defense response
			cellular component	integral to membrane
				membrane
			molecular function	protein binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.