MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene	Regulation	Gene Ontology	Class	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1093 to 1142 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
Junctophilin-1 (Junctophilin type 1) (JP-1). [Uniprot/SWISSPROT;Acc:Q9HDC5]	3.39764	down	biological_process	biological process
			integral to membrane	cellular component
			junctional membrane complex
			membrane
			microsome
			molecular_function	molecular function
			muscle development	biological process
			sarcoplasmic reticulum	cellular component
			structural constituent of muscle	molecular function
			Z disc	cellular component
Kelch-like protein 34. [Uniprot/SWISSPROT;Acc:Q8N239]	1.21698	up	electron transport	biological process
			metabolic process
			oxidoreductase activity	molecular function
			protein binding
Keratin-associated protein 19-2. [Uniprot/SWISSPROT;Acc:Q3LHN2]	1.69153	down	intermediate filament	cellular component
Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein). [Uniprot/SWISSPROT;Acc:Q9HA64]	1.18141		kinase activity	molecular function
			transferase activity
KRAB-A domain containing 1 (KRBA1), mRNA [RefSeq_dna;Acc:NM_032534]	1.66123	up	G-protein coupled receptor protein signaling pathway	biological process
			intracellular	cellular component
			membrane
			muscarinic acetylcholine receptor activity	molecular function
			nucleic acid binding
			regulation of transcription, DNA-dependent	biological process
Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor). [Uniprot/SWISSPROT;Acc:Q96MU8]	3.89584		cell communication
			integral to membrane	cellular component
			membrane
			membrane fraction
			molecular_function	molecular function
			Wnt receptor signaling pathway	biological process
LAG1 longevity assurance homolog 4. [Uniprot/SWISSPROT;Acc:Q9HA82]	1.50206		ceramide biosynthetic process
			endoplasmic reticulum	cellular component
			integral to membrane
			lipid biosynthetic process	biological process
			membrane	cellular component
			nucleus
			regulation of transcription, DNA-dependent	biological process
			sequence-specific DNA binding	molecular function
			transcription factor activity
Lariat debranching enzyme (EC 3.1.-.-). [Uniprot/SWISSPROT;Acc:Q9UK59]	1.37411		hydrolase activity
			hydrolase activity, acting on ester bonds
			metal ion binding
			mRNA processing	biological process
			nuclear mRNA splicing, via spliceosome
			nucleus	cellular component
			RNA lariat debranching enzyme activity	molecular function
			RNA splicing, via transesterification reactions	biological process
leucine-rich repeat neuronal 6A [RefSeq_peptide;Acc:NP_116197]	2.79087	down	defense response
			integral to membrane	cellular component
			membrane
			protein binding	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.