MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Regulation	description	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 951 to 1000 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
1.37411	up	Lariat debranching enzyme (EC 3.1.-.-). [Uniprot/SWISSPROT;Acc:Q9UK59]	hydrolase activity	molecular function
			hydrolase activity, acting on ester bonds
			metal ion binding
			mRNA processing	biological process
			nuclear mRNA splicing, via spliceosome
			nucleus	cellular component
			RNA lariat debranching enzyme activity	molecular function
			RNA splicing, via transesterification reactions	biological process
1.37553		NULL	peptidyl-prolyl cis-trans isomerase activity	molecular function
			protein folding	biological process
1.37801		Glycerophosphodiester phosphodiesterase domain-containing protein 2 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 3) (Osteoblast differentiation promoting factor). [Uniprot/SWISSPROT;Acc:Q9HCC8]	cytoplasm	cellular component
			cytoskeleton
			glycerol metabolic process	biological process
			glycerophosphodiester phosphodiesterase activity	molecular function
			hydrolase activity
			integral to membrane	cellular component
			membrane
			metabolic process	biological process
1.39878		ATPase family AAA domain-containing protein 2B. [Uniprot/SWISSPROT;Acc:Q9ULI0]	ATP binding	molecular function
			nucleoside-triphosphatase activity
			nucleotide binding
1.40093		NULL	protein binding
1.40451	down	COX16-like protein C14orf112, mitochondrial precursor. [Uniprot/SWISSPROT;Acc:Q9P0S2]	integral to membrane	cellular component
			membrane
			mitochondrion
1.40552		Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14). [Uniprot/SWISSPROT;Acc:Q9UN76]	amino acid metabolic process	biological process
			amino acid transport
			amino acid transporter activity	molecular function
			dicarboxylic acid transport	biological process
			integral to plasma membrane	cellular component
			membrane
			neurotransmitter transport	biological process
			neurotransmitter:sodium symporter activity	molecular function
			sodium:dicarboxylate symporter activity
			symporter activity
1.40602	up	GTP-binding protein SAR1a (COPII-associated small GTPase). [Uniprot/SWISSPROT;Acc:Q9NR31]	cytoplasm	cellular component
			endoplasmic reticulum
			ER to Golgi vesicle-mediated transport	biological process
			Golgi apparatus	cellular component
			GTP binding	molecular function
			GTPase activity
			intracellular	cellular component
			intracellular protein transport	biological process
			nucleotide binding	molecular function
			small GTPase mediated signal transduction	biological process
1.40749		collagen, type XXVII, alpha 1 [RefSeq_peptide;Acc:NP_116277]	cell adhesion
			collagen	cellular component
			cytoplasm
			dopamine receptor activity	molecular function
			extracellular matrix structural constituent

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.