MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Regulation	Ratio	Gene Ontology	description	Accession	Class	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 655 to 704 of 2667 in total

Regulation  : down

Ratio	Gene Ontology	description	Class
1.693	iron-sulfur cluster binding	CDK5 regulatory subunit associated protein 1-like 1 [RefSeq_peptide;Acc:NP_060244]	molecular function
	metabolic process		biological process
1.69658	beta-galactoside alpha-2,3-sialyltransferase activity	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase (EC 2.4.99.-) (Beta-galactoside alpha-2,3-sialyltransferase) (Alpha 2,3-sialyltransferase IV) (Alpha 2,3-ST) (Gal-NAc6S) (STZ) (SIAT4-C) (ST3Gal III) (SAT-3) (ST-4). [Uniprot/SWISSPROT;Acc:Q11206]	molecular function
	Golgi apparatus		cellular component
	integral to Golgi membrane
	integral to membrane
	membrane
	protein amino acid glycosylation		biological process
	sialyltransferase activity		molecular function
	transferase activity, transferring glycosyl groups
1.72628	DNA repair	Coiled-coil domain-containing protein 108. [Uniprot/SWISSPROT;Acc:Q6ZU64]	biological process
	integral to membrane		cellular component
	membrane
	methylated-DNA-[protein]-cysteine S-methyltransferase activity		molecular function
	structural molecule activity
1.72656	ER overload response	protein phosphatase 1, regulatory subunit 15B [RefSeq_peptide;Acc:NP_116222]	biological process
	protein phosphatase type 1 complex		cellular component
	protein serine/threonine phosphatase activity		molecular function
	response to hydrogen peroxide		biological process
	response to oxidative stress
1.73211	ATP binding	Antigen KI-67. [Uniprot/SWISSPROT;Acc:P46013]	molecular function
	cell cycle		biological process
	cell proliferation
	chromosome, pericentric region		cellular component
	condensed chromosome
	cytoplasm
	meiosis		biological process
	nucleolus		cellular component
	nucleotide binding		molecular function
	nucleus		cellular component
	protein binding		molecular function
	regulation of progression through cell cycle		biological process
1.74736	cytoplasm	Proline-serine-threonine phosphatase-interacting protein 2. [Uniprot/SWISSPROT;Acc:Q9H939]	cellular component
	membrane
1.75846	amino acid metabolic process	Cystinosin. [Uniprot/SWISSPROT;Acc:O60931]	biological process
	integral to membrane		cellular component
	L-cystine transport		biological process
	L-cystine transporter activity		molecular function
	lysosomal membrane		cellular component
	lysosome
	membrane
	transport		biological process
1.76583	aminopeptidase activity	leukocyte-derived arginine aminopeptidase [RefSeq_peptide;Acc:NP_071745]	molecular function
	antigen processing and presentation of endogenous peptide antigen via MHC class I		biological process
	blood pressure regulation
	endoplasmic reticulum lumen		cellular component
	membrane alanyl aminopeptidase activity		molecular function
	metallopeptidase activity
	N-terminal arginine aminopeptidase activity
	N-terminal lysine aminopeptidase activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.