MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Regulation	description	Gene Ontology	Class	Minimum Ratio	Accession	Gene	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 551 to 600 of 1501 in total

Regulation  : up

Ratio	description	Gene Ontology	Class
1.40749	collagen, type XXVII, alpha 1 [RefSeq_peptide;Acc:NP_116277]	collagen	cellular component
		cytoplasm
		dopamine receptor activity	molecular function
		extracellular matrix structural constituent
		G-protein coupled receptor protein signaling pathway	biological process
		integral to membrane	cellular component
		phosphate transport	biological process
		structural constituent of cell wall	molecular function
		structural molecule activity
1.42264	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (hLark). [Uniprot/SWISSPROT;Acc:Q9BWF3]	cytoplasm	cellular component
		homoiothermy	biological process
		ice binding	molecular function
		intracellular	cellular component
		metal ion binding	molecular function
		mRNA processing	biological process
		nucleic acid binding	molecular function
		nucleotide binding
		nucleus	cellular component
		response to freezing	biological process
		ribosome	cellular component
		RNA binding	molecular function
		RNA splicing	biological process
		structural constituent of ribosome	molecular function
		translation	biological process
		type I hypersensitivity
		zinc ion binding	molecular function
1.44789	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B). [Uniprot/SWISSPROT;Acc:Q16633]	DNA binding
		humoral immune response	biological process
		nucleus	cellular component
		protein binding	molecular function
		regulation of transcription, DNA-dependent	biological process
		transcription
		transcription coactivator activity	molecular function
		transcription from RNA polymerase II promoter	biological process
1.45148	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372). [Uniprot/SWISSPROT;Acc:Q14789]	DNA binding	molecular function
		ER-Golgi intermediate compartment	cellular component
		Golgi apparatus
		Golgi membrane
		Golgi organization and biogenesis	biological process
		Golgi stack	cellular component
		integral to membrane
		membrane
		nucleus
		protein binding	molecular function
		regulation of transcription, DNA-dependent	biological process
		vesicle-mediated transport
1.45314	NULL	DNA binding	molecular function
1.45624	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2). [Uniprot/SWISSPROT;Acc:Q16621]	circulation	biological process
		DNA binding	molecular function
		hemostasis	biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.