Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio Regulation Gene Ontology description Accession Class Gene Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 51 to 100 of 2667 in total

Ratio	Regulation	Gene Ontology	description	Class	
1.11519	up	translation initiation factor activity	eukaryotic translation initiation factor 4E family member 1B (EIF4E1B), mRNA [Source:RefSeq_dna;Acc:NM_001099408]	molecular function	
1.11519	up	translational initiation	eukaryotic translation initiation factor 4E family member 1B (EIF4E1B), mRNA [Source:RefSeq_dna;Acc:NM_001099408]	biological process	
1.11956	down	Golgi apparatus	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	cellular component	
1.11956	down	integral to Golgi membrane	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	cellular component	
1.11956	down	integral to membrane	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	cellular component	
1.11956	down	membrane	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	cellular component	
1.11956	down	molecular_function	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	molecular function	
1.11956	down	retrograde vesicle-mediated transport, Golgi to ER	Protein RER1. [Source:Uniprot/SWISSPROT;Acc:O15258]	biological process	
1.12417	up	enzyme binding	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	
1.12417	up	membrane	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	cellular component	
1.12417	up	protein heterodimerization activity	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	
1.12417	up	protein homooligomerization	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	biological process	
1.12417	up	protein localization	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	biological process	
1.12417	up	response to metal ion	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	biological process	
1.12417	up	retinoic acid receptor binding	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	
1.12417	up	retinoid-X receptor activity	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	
1.12417	up	thyroid hormone receptor binding	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	
1.12417	up	thyroid hormone receptor coactivator activity	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	
1.12417	up	vitamin D receptor binding	Protein CutA precursor (Brain acetylcholinesterase putative membrane anchor) (Acetylcholinesterase-associated protein). [Source:Uniprot/SWISSPROT;Acc:O60888]	molecular function	
1.1243	down	DNA binding	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	molecular function	
1.1243	down	intracellular	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	cellular component	
1.1243	down	metal ion binding	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	molecular function	
1.1243	down	nucleic acid binding	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	molecular function	
1.1243	down	nucleus	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	cellular component	
1.1243	down	regulation of transcription, DNA-dependent	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	biological process	
1.1243	down	transcription	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	biological process	
1.1243	down	zinc ion binding	Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30]	molecular function	
1.13007	up	anion transport	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	biological process	
1.13007	up	G-protein coupled receptor protein signaling pathway	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	biological process	
1.13007	up	histamine receptor activity	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	
1.13007	up	inorganic anion exchanger activity	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	
1.13007	up	integral to membrane	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	cellular component	
1.13007	up	intracellular	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	cellular component	
1.13007	up	membrane	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	cellular component	
1.13007	up	metal ion binding	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	
1.13007	up	nucleic acid binding	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	
1.13007	up	nucleus	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	cellular component	
1.13007	up	regulation of transcription, DNA-dependent	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	biological process	
1.13007	up	transcription factor activity	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	
1.13007	up	zinc ion binding	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	molecular function	
1.13541	down	blood coagulation	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	biological process	
1.13541	down	calcium ion binding	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	molecular function	
1.13541	down	cell adhesion	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	biological process	
1.13541	down	extracellular region	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	cellular component	
1.13541	down	membrane	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	cellular component	
1.13541	down	protein binding	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	molecular function	
1.13541	down	regulation of growth	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	biological process	
1.13541	down	structural molecule activity	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	molecular function	
1.13541	down	transmembrane receptor activity	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Source:Uniprot/SWISSPROT;Acc:Q99435]	molecular function	
1.14311	down	cytoplasm	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	cellular component	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/