MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	Gene Ontology	description	Class	Accession	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 318 to 367 of 2667 in total

Ratio	Regulation	Gene Ontology	description	Class
1.19545	up	hormone activity	Deoxyribonuclease-2-alpha precursor (EC 3.1.22.1) (Deoxyribonuclease II alpha) (DNase II alpha) (Acid DNase) (Lysosomal DNase II) (R31240_2). [Uniprot/SWISSPROT;Acc:O00115]	molecular function
		hydrolase activity
		lysosome		cellular component
		multicellular organismal development		biological process
		protein binding		molecular function
1.20102		apoptosis	Metalloreductase STEAP3 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde) (Dudulin-2). [Uniprot/SWISSPROT;Acc:Q658P3]	biological process
		cell cycle
		copper ion binding		molecular function
		electron transport		biological process
		endosome		cellular component
		FAD binding		molecular function
		ferric-chelate reductase activity
		integral to membrane		cellular component
		ion transport		biological process
		iron ion binding		molecular function
		iron ion transport		biological process
		membrane		cellular component
		metal ion binding		molecular function
		oxidoreductase activity
		plasma membrane		cellular component
1.20481	down	biological_process	Neurosecretory protein VGF precursor. [Uniprot/SWISSPROT;Acc:O15240]	biological process
		cellular_component		cellular component
		cytoplasmic vesicle
		generation of precursor metabolites and energy		biological process
		growth factor activity		molecular function
		neuropeptide hormone activity
		ovarian follicle development		biological process
		sexual reproduction
1.20619		ATP binding	Sodium/potassium-transporting ATPase subunit alpha-4 (EC 3.6.3.9) (Sodium pump subunit alpha-4) (Na(+)/K(+) ATPase alpha-4 subunit). [Uniprot/SWISSPROT;Acc:Q13733]	molecular function
		ATP hydrolysis coupled proton transport		biological process
		ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism		molecular function
		catalytic activity
		cation transport		biological process
		GABA-B receptor activity		molecular function
		hydrogen ion homeostasis		biological process
		hydrolase activity		molecular function
		hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
		integral to membrane		cellular component
		magnesium ion binding		molecular function
		membrane		cellular component
		metabolic process		biological process
		monovalent inorganic cation transport
		monovalent inorganic cation transporter activity		molecular function
		nucleotide binding
		potassium ion binding
		potassium ion transport		biological process
		proton transport
		sodium ion binding		molecular function
		sodium ion transport		biological process
		sodium:potassium-exchanging ATPase activity		molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.