MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Regulation	description	Accession	Gene Ontology	Class	Minimum Ratio	Gene	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2501 to 2550 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
4.62042	down	Leukocyte antigen CD37 (Tetraspanin-26) (Tspan-26). [Uniprot/SWISSPROT;Acc:P11049]	integral to membrane	cellular component
			integral to plasma membrane
			membrane
			plasma membrane
			protein amino acid N-linked glycosylation	biological process
			visual perception
4.67988	up	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3). [Uniprot/SWISSPROT;Acc:P22001]	delayed rectifier potassium channel activity	molecular function
			dicarboxylic acid transport	biological process
			integral to membrane	cellular component
			ion channel activity	molecular function
			ion transport	biological process
			membrane	cellular component
			membrane fraction
			outward rectifier potassium channel activity	molecular function
			potassium ion binding
			potassium ion transport	biological process
			protein binding	molecular function
			sodium:dicarboxylate symporter activity
			voltage-gated ion channel activity
			voltage-gated potassium channel activity
			voltage-gated potassium channel complex	cellular component
4.69231	down	Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (Polymorphic arylamine N-acetyltransferase) (PNAT) (N- acetyltransferase type 2) (NAT-2). [Uniprot/SWISSPROT;Acc:P11245]	acetyltransferase activity	molecular function
			arylamine N-acetyltransferase activity
			cytoplasm	cellular component
			metabolic process	biological process
			transferase activity	molecular function
4.71132		Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase) (Pyruvate kinase 1). [Uniprot/SWISSPROT;Acc:P30613]	cellular_component	cellular component
			glycolysis	biological process
			magnesium ion binding	molecular function
			potassium ion binding
			pyruvate kinase activity
			response to other organism	biological process
			transferase activity	molecular function
4.87049	up	zinc finger, FYVE domain containing 26 [RefSeq_peptide;Acc:NP_056161]	intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			zinc ion binding
4.90535	down	DAZ-associated protein 2 (Deleted in azoospermia-associated protein 2). [Uniprot/SWISSPROT;Acc:Q15038]	protein binding
4.93372		Ankyrin repeat and SOCS box protein 12 (ASB-12). [Uniprot/SWISSPROT;Acc:Q8WXK4]	intracellular signaling cascade	biological process
5.01332	up	Ufm1-specific protease 2 (EC 3.4.22.-) (UfSP2). [Uniprot/SWISSPROT;Acc:Q9NUQ7]	cysteine-type peptidase activity	molecular function
			thiolester hydrolase activity
			ubiquitin cycle	biological process
5.19755		Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Uniprot/SWISSPROT;Acc:Q96A54]	fatty acid oxidation
			hormone binding	molecular function
			hormone-mediated signaling	biological process
			identical protein binding	molecular function
			integral to membrane	cellular component
			lipid metabolic process	biological process
			membrane	cellular component
			protein heterodimerization activity	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.