MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Accession	Regulation	Ratio	description	Class	Gene Ontology	Minimum Ratio	Gene	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2069 to 2118 of 2667 in total

Regulation  : up

Ratio	description	Class	Gene Ontology
1.89308	Ras-related protein Rab-36. [Uniprot/SWISSPROT;Acc:O95755]	molecular function	GTPase activity
			nucleotide binding
			protein binding
1.93863	Olfactory receptor 2B2 (Olfactory receptor 6-1) (OR6-1) (Hs6M1-10). [Uniprot/SWISSPROT;Acc:Q9GZK3]	biological process	G-protein coupled receptor protein signaling pathway
			response to stimulus
			sensory perception of smell
			signal transduction
		cellular component	integral to membrane
			membrane
		molecular function	olfactory receptor activity
			receptor activity
			rhodopsin-like receptor activity
1.93995	Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Uniprot/SWISSPROT;Acc:Q92785]	biological process	apoptosis
			induction of apoptosis by extracellular signals
			regulation of transcription, DNA-dependent
			transcription
		cellular component	cytoplasm
			intracellular
			nucleus
		molecular function	metal ion binding
			nucleic acid binding
			protein binding
			zinc ion binding
1.95876	Ras-related protein Rab-17. [Uniprot/SWISSPROT;Acc:Q9H0T7]	biological process	intracellular protein transport
			nucleocytoplasmic transport
			protein transport
			signal transduction
			small GTPase mediated signal transduction
		cellular component	intracellular
		molecular function	GTP binding
			GTPase activity
			nucleotide binding
			protein binding
1.96673	Signal peptidase complex catalytic subunit SEC11C (EC 3.4.-.-) (SEC11 homolog C) (SEC11-like protein 3) (Microsomal signal peptidase 21 kDa subunit) (SPase 21 kDa subunit) (SPC21). [Uniprot/SWISSPROT;Acc:Q9BY50]	biological process	proteolysis
			signal peptide processing
		cellular component	endoplasmic reticulum
			integral to membrane
			membrane
			microsome
		molecular function	peptidase activity
			serine-type peptidase activity
1.98149	CD40 ligand (CD40-L) (Tumor necrosis factor ligand superfamily member 5) (TNF-related activation protein) (TRAP) (T cell antigen Gp39) (CD154 antigen) [Contains: CD40 ligand, membrane form; CD40 ligand, soluble form]. [Uniprot/SWISSPROT;Acc:P29965]	biological process	anti-apoptosis
			B cell differentiation
			B cell proliferation
			immune response
			inflammatory response
			isotype switching
			leukocyte adhesion
			platelet activation
			regulation of immunoglobulin secretion

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.