MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Regulation	Ratio	description	Accession	Gene Ontology	Class	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2051 to 2100 of 2667 in total

Regulation  : up

Ratio	description	Gene Ontology	Class
1.83601	coiled-coil domain containing 90A [RefSeq_peptide;Acc:NP_001026883]	mitochondrion	cellular component
1.86433	CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4). [Uniprot/SWISSPROT;Acc:Q8IZR5]	ATP binding	molecular function
		ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
		cation transport	biological process
		chemotaxis
		cytokine activity	molecular function
		extracellular space	cellular component
		integral to membrane
		membrane
1.89308	Ras-related protein Rab-36. [Uniprot/SWISSPROT;Acc:O95755]	Golgi apparatus
		GTP binding	molecular function
		GTPase activity
		intracellular	cellular component
		intracellular protein transport	biological process
		membrane	cellular component
		nucleocytoplasmic transport	biological process
		nucleotide binding	molecular function
		protein binding
		protein transport	biological process
		signal transduction
		small GTPase mediated signal transduction
1.93863	Olfactory receptor 2B2 (Olfactory receptor 6-1) (OR6-1) (Hs6M1-10). [Uniprot/SWISSPROT;Acc:Q9GZK3]	G-protein coupled receptor protein signaling pathway
		integral to membrane	cellular component
		membrane
		olfactory receptor activity	molecular function
		receptor activity
		response to stimulus	biological process
		rhodopsin-like receptor activity	molecular function
		sensory perception of smell	biological process
		signal transduction
1.93995	Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Uniprot/SWISSPROT;Acc:Q92785]	apoptosis
		cytoplasm	cellular component
		induction of apoptosis by extracellular signals	biological process
		intracellular	cellular component
		metal ion binding	molecular function
		nucleic acid binding
		nucleus	cellular component
		protein binding	molecular function
		regulation of transcription, DNA-dependent	biological process
		transcription
		zinc ion binding	molecular function
1.95876	Ras-related protein Rab-17. [Uniprot/SWISSPROT;Acc:Q9H0T7]	GTP binding
		GTPase activity
		intracellular	cellular component
		intracellular protein transport	biological process
		nucleocytoplasmic transport
		nucleotide binding	molecular function
		protein binding
		protein transport	biological process
		signal transduction

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.