MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Regulation	description	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1851 to 1900 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
2.33107	down	F-box only protein 15. [Uniprot/SWISSPROT;Acc:Q8NCQ5]	SCF ubiquitin ligase complex	cellular component
			ubiquitin cycle	biological process
2.37788	up	Coiled-coil domain-containing protein 83. [Uniprot/SWISSPROT;Acc:Q8IWF9]	structural molecule activity	molecular function
			viral capsid	cellular component
2.43098		Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2). [Uniprot/SWISSPROT;Acc:Q9H1P3]	lipid transport	biological process
			steroid metabolic process
2.44552	down	Guanine nucleotide-binding protein alpha-14 subunit (G-protein alpha subunit 14). [Uniprot/SWISSPROT;Acc:O95837]	G-protein coupled receptor protein signaling pathway
			GTP binding	molecular function
			GTPase activity
			guanyl nucleotide binding
			heterotrimeric G-protein complex	cellular component
			nucleotide binding	molecular function
			plasma membrane	cellular component
			protein amino acid ADP-ribosylation	biological process
			signal transducer activity	molecular function
			signal transduction	biological process
2.45383		40S ribosomal protein S2 (S4) (LLRep3 protein). [Uniprot/SWISSPROT;Acc:P15880]	cytosolic small ribosomal subunit (sensu Eukaryota)	cellular component
			intracellular
			ribosome
			RNA binding	molecular function
			small ribosomal subunit	cellular component
			structural constituent of ribosome	molecular function
			translation	biological process
2.45764	up	zinc transporter like 2 [RefSeq_peptide;Acc:NP_598003]	cation transport
			cation transporter activity	molecular function
			cytoplasmic membrane-bound vesicle	cellular component
			Golgi apparatus
			membrane
			protein binding	molecular function
			zinc ion transport	biological process
			zinc ion transporter activity	molecular function
2.45875		ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19). [Uniprot/SWISSPROT;Acc:Q8TE59]	extracellular matrix	cellular component
			intracellular
			metal ion binding	molecular function
			metalloendopeptidase activity
			metallopeptidase activity
			nucleic acid binding
			peptidase activity
			proteinaceous extracellular matrix	cellular component
			proteolysis	biological process
			zinc ion binding	molecular function
2.48474		BET1 homolog (Golgi vesicular membrane-trafficking protein p18) (hBET1). [Uniprot/SWISSPROT;Acc:O15155]	endoplasmic reticulum	cellular component
			ER to Golgi vesicle-mediated transport	biological process
			Golgi apparatus	cellular component
			Golgi membrane
			integral to membrane
			membrane
			protein binding	molecular function
			protein transport	biological process
2.49031		Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta). [Uniprot/SWISSPROT;Acc:Q99767]	nervous system development

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.