MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	description	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1619 to 1668 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
1.83496	up	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation). [Uniprot/SWISSPROT;Acc:Q92636]	ceramide metabolic process	biological process
			cytoplasm	cellular component
			receptor signaling protein activity	molecular function
			signal transduction	biological process
			soluble fraction	cellular component
1.83601		coiled-coil domain containing 90A [RefSeq_peptide;Acc:NP_001026883]	G-protein coupled receptor protein signaling pathway	biological process
			integral to membrane	cellular component
			membrane
			mitochondrion
1.86204	down	Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494). [Uniprot/SWISSPROT;Acc:Q8NAM6]	intracellular
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			transcription
			transcription factor activity	molecular function
			zinc ion binding
1.86433	up	CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine- like factor superfamily member 4). [Uniprot/SWISSPROT;Acc:Q8IZR5]	ATP binding
			ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
			cation transport	biological process
			chemotaxis
			cytokine activity	molecular function
			extracellular space	cellular component
			integral to membrane
			membrane
1.89168	down	Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Uniprot/SWISSPROT;Acc:O95125]	DNA binding	molecular function
			intracellular	cellular component
			lipid metabolic process	biological process
			metal ion binding	molecular function
			negative regulation of transcription from RNA polymerase II promoter	biological process
			nucleic acid binding	molecular function
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			specific RNA polymerase II transcription factor activity	molecular function
			transcription	biological process
			transcription factor activity	molecular function
			zinc ion binding
1.89308	up	Ras-related protein Rab-36. [Uniprot/SWISSPROT;Acc:O95755]	Golgi apparatus	cellular component
			GTP binding	molecular function
			GTPase activity
			intracellular	cellular component
			intracellular protein transport	biological process
			membrane	cellular component
			nucleocytoplasmic transport	biological process
			nucleotide binding	molecular function
			protein binding
			protein transport	biological process
			signal transduction
			small GTPase mediated signal transduction
1.93863		Olfactory receptor 2B2 (Olfactory receptor 6-1) (OR6-1) (Hs6M1-10). [Uniprot/SWISSPROT;Acc:Q9GZK3]	G-protein coupled receptor protein signaling pathway

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.