MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	Ratio	description	Minimum Ratio	Class	Gene Ontology	Accession	Gene	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1 to 9 of 9 in total

Class  : molecular function
Gene Ontology  : structural molecule activity

Regulation	Ratio	description
down	1.13541	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2). [Uniprot/SWISSPROT;Acc:Q99435]
	1.54676	WAS protein homology region 2 domain containing 1 [RefSeq_peptide;Acc:NP_001073904]
	1.72628	Coiled-coil domain-containing protein 108. [Uniprot/SWISSPROT;Acc:Q6ZU64]
	3.05037	Thrombospondin-4 precursor. [Uniprot/SWISSPROT;Acc:P35443]
up	1.15279	Podocalyxin-like protein 2 precursor (Endoglycan). [Uniprot/SWISSPROT;Acc:Q9NZ53]
	1.21657	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1). [Uniprot/SWISSPROT;Acc:Q99719]
	1.40749	collagen, type XXVII, alpha 1 [RefSeq_peptide;Acc:NP_116277]
	1.75026	Claudin-11 (Oligodendrocyte-specific protein). [Uniprot/SWISSPROT;Acc:O75508]
	2.37788	Coiled-coil domain-containing protein 83. [Uniprot/SWISSPROT;Acc:Q8IWF9]

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.