MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
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description	p	Ratio	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 1 to 50 of 239 in total

description	p	Ratio	neuronal
7S RNA binding	0.0395988	up	no value
acetyltransferase activity	0.00774091
activation of MAPKK activity	0.0395988
adult heart development
aldehyde dehydrogenase [NAD(P)+] activity	0.00383965
amino acid metabolic process	0.0404804
anatomical structure morphogenesis	0.0101128
anion exchanger activity	0.00235127
anion transport	0.0262113
antigen binding	0.00127674	down
antiporter activity	0.0368141	up
AP-2 adaptor complex	0.0202076
apical junction complex	0.0395988
arylamine N-acetyltransferase activity	0.00235127
ATP binding	0.00123417	down
ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	0.0202076	up
axon ensheathment	0.0395988		1
beta-galactoside alpha-2,3-sialyltransferase activity	0.0202076		no value
beta-mannosidase activity
binding	0.00803044	down
calcium channel activity	0.0473076	up
calcium channel regulator activity	0.02908		1
calmodulin binding	0.0109353		no value
camera-type eye development	0.0202076
cannabinoid receptor activity	0.0395988		1
carotenoid biosynthetic process	0.0202076		no value
catalytic activity	1.04188e-19	down
CD40 receptor binding	0.0202076	up
cell adhesion	0.0369324
cell cycle	0.00425207
cell growth	0.0493456
cell junction	0.000000005351
cell motility	0.0192954
cell proliferation	0.011406
cell-cell signaling	0.0000244289
cellular protein metabolic process	0.0395988
centrosome duplication	0.0202076
ceramide biosynthetic process	0.0395988
chromatin binding	0.0483241
chromosome, pericentric region	0.00970846
chymotrypsin activity	0.0175073	down
ciliary or flagellar motility	0.00235127	up
circulation	0.00564318
clathrin binding	0.0202076
cytoplasm	0.00000000000532447
cytoplasmic chromatin	0.0202076
cytoplasmic vesicle	0
cytoskeletal anchoring	0.0202076
delayed rectifier potassium channel activity
deoxyribonuclease II activity	0.0395988

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.