MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	p	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 72 to 121 of 239 in total

description	Ratio	p	neuronal
generation of precursor metabolites and energy	up	0.0395988	no value
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity	down	0.0040154
glycerol metabolic process	up	0.000857538
glycerophosphodiester phosphodiesterase activity		0.0127396
glycolysis	down	0.00369746
glycosaminoglycan binding	up	0.0395988
glyoxylate cycle		0.0202076
Golgi apparatus		0.0000000750539
Golgi stack	down	0.01078
growth hormone secretion	up	0.0395988
GTPase activity		0.000793622
guanyl nucleotide binding		0.00774091
hemostasis		0.0395988
histamine receptor activity		0.00383965
homoiothermy		0
hormone activity		0.023627
humoral immune response		0.0101128
ice binding		0
identical protein binding		0.00308834
inner ear morphogenesis		0.0340565
inorganic anion exchanger activity		0.0368141
integral to Golgi membrane		0.0254395
integral to membrane	down	0.000000909018
integral to peroxisomal membrane	up	0.0395988
integral to plasma membrane		0.0000520983
integrase activity	down	0.028596
intercellular junction maintenance	up	0.0395988
interleukin-1 receptor activity		0.00383965
interleukin-1 receptor complex		0.0202076
interleukin-18 receptor complex
intracellular		0.00836988
iron-sulfur cluster binding		0.0395988
kinase activity	down	0.0216681
leading edge cell differentiation	up	0.0202076
leukocyte activation
leukocyte adhesion
ligand-dependent nuclear receptor activity		0.00564318
lipid biosynthetic process		0.0156029
lipid metabolic process		0.0354267
male pronucleus		0.0202076
mannosidase activity		0.0395988
membrane		0
membrane coat		0.00383965
membrane fraction		0.0000321095
metabolic process		0.0193082
metabotropic glutamate receptor signaling pathway	down	0.00362499	1
metabotropic glutamate, GABA-B-like receptor activity		0.0111584
metal ion binding	up	0.0431445	no value
metallopeptidase activity		0.0193329
methyl-CpG binding		0.0202076

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.