MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Accession	neuronal	p

Results: HTML CSV LaTeX

Showing element 101 to 150 of 239 in total

description	Ratio	neuronal	p
interleukin-18 receptor complex	up	no value	0.0202076
intracellular			0.00836988
iron-sulfur cluster binding			0.0395988
kinase activity	down		0.0216681
leading edge cell differentiation	up		0.0202076
leukocyte activation
leukocyte adhesion
ligand-dependent nuclear receptor activity			0.00564318
lipid biosynthetic process			0.0156029
lipid metabolic process			0.0354267
male pronucleus			0.0202076
mannosidase activity			0.0395988
membrane			0
membrane coat			0.00383965
membrane fraction			0.0000321095
metabolic process			0.0193082
metabotropic glutamate receptor signaling pathway	down	1	0.00362499
metabotropic glutamate, GABA-B-like receptor activity			0.0111584
metal ion binding	up	no value	0.0431445
metallopeptidase activity			0.0193329
methyl-CpG binding			0.0202076
methylated-DNA-[protein]-cysteine S-methyltransferase activity			0.0395988
microtubule binding			0.0107462
microtubule-based movement	down		0.0206183
mitochondrial small ribosomal subunit	up		0.0395988
mitochondrion	down		0.00965867
mitosis	up		0.00504034
mitotic G2 checkpoint			0.0395988
monoamine transport
monoamine transporter activity			0.0202076
morphogenesis of an epithelium			0.0127396
mRNA transport			0.000408197
multicellular organismal development			0.00726676
myoblast fusion			0.0395988
NAD binding	down		0.00245746
negative regulation of cell growth	up		0.00664368
negative regulation of protein kinase activity			0.0368141
nervous system development		1	0.00878703
neuropeptide hormone activity			0.00115531
neuropeptide receptor activity			0.0395988
neurotransmitter:sodium symporter activity			0.0262113
nuclear organization and biogenesis		no value	0.0395988
nucleic acid binding	down		0.00000144966
nucleocytoplasmic transport	up		0.000237102
nucleoplasm			0.0108714
nucleoside transporter activity			0.00383965
nucleotide binding			0.0322278
nucleus	down		0
olfactory receptor activity		1	0.000000227862
oocyte differentiation	up	no value	0.0202076

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.