MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

p	Ratio	description	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 51 to 100 of 201 in total

Ratio  : up

p	description	neuronal
0.00664368	negative regulation of cell growth	no value
0.00670433	voltage-gated ion channel activity	1
0.00726676	multicellular organismal development	no value
0.00759448	protein serine/threonine phosphatase activity
0.00774091	acetyltransferase activity
	electron carrier activity	1
	ER-Golgi intermediate compartment	no value
	guanyl nucleotide binding
	positive regulation of body size
	retinoic acid metabolic process
0.00833399	regulation of transcription
0.00836988	intracellular
0.00878703	nervous system development	1
0.00916333	visual perception
0.00970846	chromosome, pericentric region	no value
0.0100316	potassium ion binding	1
0.0101128	anatomical structure morphogenesis	no value
	humoral immune response
0.0107462	microtubule binding
0.0108714	nucleoplasm
0.0109032	endoplasmic reticulum
0.0109353	calmodulin binding
0.011406	cell proliferation
0.0126107	positive regulation of cell proliferation
0.0127396	fibroblast growth factor receptor signaling pathway
	glycerophosphodiester phosphodiesterase activity
	morphogenesis of an epithelium
	sodium:dicarboxylate symporter activity
0.0148187	protein transport
0.0156029	dicarboxylic acid transport
	lipid biosynthetic process
0.0159483	sensory perception of sound	1
0.0168307	protein modification process	no value
0.0189851	response to oxidative stress
0.0192954	cell motility
	extracellular matrix
0.0193082	metabolic process
0.0193329	metallopeptidase activity
0.0202076	AP-2 adaptor complex
	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
	beta-galactoside alpha-2,3-sialyltransferase activity
	beta-mannosidase activity
	camera-type eye development
	carotenoid biosynthetic process
	CD40 receptor binding
	centrosome duplication
	clathrin binding
	cytoplasmic chromatin
	cytoskeletal anchoring
	delayed rectifier potassium channel activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.