Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
p Ratio description Accession neuronal
Results: HTML CSV LaTeX Showing element 1 to 38 of 38 in total 
Ratio: down

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\hline
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p\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
description\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
neuronal\vspace{3pt}}\\
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0\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
nucleus\vspace{3pt}}&\multirow{4}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
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1.04188e-19\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
catalytic activity\vspace{3pt}}&\\\cline{1-2}
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4.41122e-18\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
extracellular space\vspace{3pt}}&\\\cline{1-2}
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0.0000000000369233\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
receptor activity\vspace{3pt}}&\\\hline
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olfactory receptor activity\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
1\vspace{3pt}}\\\hline
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structural constituent of ribosome\vspace{3pt}}&\multirow{14}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
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integral to membrane\vspace{3pt}}&\\\cline{1-2}
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external side of plasma membrane\vspace{3pt}}&\\\cline{1-2}
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metabotropic glutamate receptor signaling pathway\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
1\vspace{3pt}}\\\hline
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glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity\vspace{3pt}}&\\\cline{1-2}
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regulation of transcription, DNA-dependent\vspace{3pt}}&\\\cline{1-2}
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electron transport\vspace{3pt}}&\\\hline
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transferase activity\vspace{3pt}}&\\\hline
nd{longtable}

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.

 - Accession is the GO accession key. 

 - Part of neuralk circuitery.
- http://analysis.yellowcouch.org/